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Page 1
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.
De Jager PL, Jia X, Wang J, de Bakker PI, Ottoboni L, Aggarwal NT, Piccio L, Raychaudhuri S, Tran D, Aubin C, Briskin R, Romano S; International MS Genetics Consortium; Baranzini SE, McCauley JL, Pericak-Vance MA, Haines JL, Gibson RA, Naeglin Y, Uitdehaag B, Matthews PM, Kappos L, Polman C, McArdle WL, Strachan DP, Evans D, Cross AH, Daly MJ, Compston A, Sawcer SJ, Weiner HL, Hauser SL, Hafler DA, Oksenberg JR. De Jager PL, et al. Nat Genet. 2009 Jul;41(7):776-82. doi: 10.1038/ng.401. Epub 2009 Jun 14. Nat Genet. 2009. PMID: 19525953 Free PMC article.
The role of the CD58 locus in multiple sclerosis.
De Jager PL, Baecher-Allan C, Maier LM, Arthur AT, Ottoboni L, Barcellos L, McCauley JL, Sawcer S, Goris A, Saarela J, Yelensky R, Price A, Leppa V, Patterson N, de Bakker PI, Tran D, Aubin C, Pobywajlo S, Rossin E, Hu X, Ashley CW, Choy E, Rioux JD, Pericak-Vance MA, Ivinson A, Booth DR, Stewart GJ, Palotie A, Peltonen L, Dubois B, Haines JL, Weiner HL, Compston A, Hauser SL, Daly MJ, Reich D, Oksenberg JR, Hafler DA. De Jager PL, et al. Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5264-9. doi: 10.1073/pnas.0813310106. Epub 2009 Feb 23. Proc Natl Acad Sci U S A. 2009. PMID: 19237575 Free PMC article.
Cytometric profiling in multiple sclerosis uncovers patient population structure and a reduction of CD8low cells.
De Jager PL, Rossin E, Pyne S, Tamayo P, Ottoboni L, Viglietta V, Weiner M, Soler D, Izmailova E, Faron-Yowe L, O'Brien C, Freeman S, Granados S, Parker A, Roubenoff R, Mesirov JP, Khoury SJ, Hafler DA, Weiner HL. De Jager PL, et al. Brain. 2008 Jul;131(Pt 7):1701-11. doi: 10.1093/brain/awn118. Epub 2008 Jun 21. Brain. 2008. PMID: 18567923 Free PMC article.
Genetic variation in the IL7RA/IL7 pathway increases multiple sclerosis susceptibility.
Zuvich RL, McCauley JL, Oksenberg JR, Sawcer SJ, De Jager PL; International Multiple Sclerosis Genetics Consortium; Aubin C, Cross AH, Piccio L, Aggarwal NT, Evans D, Hafler DA, Compston A, Hauser SL, Pericak-Vance MA, Haines JL. Zuvich RL, et al. Hum Genet. 2010 Mar;127(5):525-35. doi: 10.1007/s00439-010-0789-4. Epub 2010 Jan 30. Hum Genet. 2010. PMID: 20112030 Free PMC article.
A second major histocompatibility complex susceptibility locus for multiple sclerosis.
Yeo TW, De Jager PL, Gregory SG, Barcellos LF, Walton A, Goris A, Fenoglio C, Ban M, Taylor CJ, Goodman RS, Walsh E, Wolfish CS, Horton R, Traherne J, Beck S, Trowsdale J, Caillier SJ, Ivinson AJ, Green T, Pobywajlo S, Lander ES, Pericak-Vance MA, Haines JL, Daly MJ, Oksenberg JR, Hauser SL, Compston A, Hafler DA, Rioux JD, Sawcer S. Yeo TW, et al. Ann Neurol. 2007 Mar;61(3):228-36. doi: 10.1002/ana.21063. Ann Neurol. 2007. PMID: 17252545 Free PMC article.
A high-density admixture map for disease gene discovery in african americans.
Smith MW, Patterson N, Lautenberger JA, Truelove AL, McDonald GJ, Waliszewska A, Kessing BD, Malasky MJ, Scafe C, Le E, De Jager PL, Mignault AA, Yi Z, De The G, Essex M, Sankale JL, Moore JH, Poku K, Phair JP, Goedert JJ, Vlahov D, Williams SM, Tishkoff SA, Winkler CA, De La Vega FM, Woodage T, Sninsky JJ, Hafler DA, Altshuler D, Gilbert DA, O'Brien SJ, Reich D. Smith MW, et al. Am J Hum Genet. 2004 May;74(5):1001-13. doi: 10.1086/420856. Epub 2004 Apr 14. Am J Hum Genet. 2004. PMID: 15088270 Free PMC article.