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Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy.
Chhabra Y, Fane ME, Pramod S, Hüser L, Zabransky DJ, Wang V, Dixit A, Zhao R, Kumah E, Brezka ML, Truskowski K, Nandi A, Marino-Bravante GE, Carey AE, Gour N, Maranto DA, Rocha MR, Harper EI, Ruiz J, Lipson EJ, Jaffee EM, Bibee K, Sunshine JC, Ji H, Weeraratna AT. Chhabra Y, et al. Cell. 2024 Oct 17;187(21):6016-6034.e25. doi: 10.1016/j.cell.2024.08.013. Epub 2024 Sep 6. Cell. 2024. PMID: 39243764
Fibroblasts in the Aged Pancreas Drive Pancreatic Cancer Progression.
Zabransky DJ, Chhabra Y, Fane ME, Kartalia E, Leatherman JM, Hüser L, Zimmerman JW, Delitto D, Han S, Armstrong TD, Charmsaz S, Guinn S, Pramod S, Thompson ED, Hughes SJ, O'Connell J, Egan JM, Jaffee EM, Weeraratna AT. Zabransky DJ, et al. Cancer Res. 2024 Apr 15;84(8):1221-1236. doi: 10.1158/0008-5472.CAN-24-0086. Cancer Res. 2024. PMID: 38330147
Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis.
Alicea GM, Patel P, Portuallo ME, Fane ME, Wei M, Chhabra Y, Dixit A, Carey AE, Wang V, Rocha MR, Behera R, Speicher DW, Tang HY, Kossenkov AV, Rebecca VW, Wirtz D, Weeraratna AT. Alicea GM, et al. Cancer Res Commun. 2024 Aug 1;4(8):1908-1918. doi: 10.1158/2767-9764.CRC-23-0176. Cancer Res Commun. 2024. PMID: 39007351 Free PMC article.