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IL-15-secreting CAR natural killer cells directed toward the pan-cancer target CD70 eliminate both cancer cells and cancer-associated fibroblasts.
Van den Eynde A, Gehrcken L, Verhezen T, Lau HW, Hermans C, Lambrechts H, Flieswasser T, Quatannens D, Roex G, Zwaenepoel K, Marcq E, Joye P, Cardenas De La Hoz E, Deben C, Gasparini A, Montay-Gruel P, Le Compte M, Lion E, Lardon F, Van Laere S, Siozopoulou V, Campillo-Davo D, De Waele J, Pauwels P, Jacobs J, Smits E, Van Audenaerde JRM. Van den Eynde A, et al. J Hematol Oncol. 2024 Feb 9;17(1):8. doi: 10.1186/s13045-024-01525-w. J Hematol Oncol. 2024. PMID: 38331849 Free PMC article.
BACKGROUND: It remains challenging to obtain positive outcomes with chimeric antigen receptor (CAR)-engineered cell therapies in solid malignancies, like colorectal cancer (CRC) and pancreatic ductal adenocarcinoma (PDAC). A major obstacle is the lack of targetable surface …
BACKGROUND: It remains challenging to obtain positive outcomes with chimeric antigen receptor (CAR)-engineered cell therapies in solid malig …
Dutch Translation of the Yost Self-Report Lower Extremity Lymphedema Screening Questionnaire in Women.
Decorte T, Van Calster C, Randon C, Van Besien V, Ketels M, Vanden Bossche L, De Schryver M, Monten C. Decorte T, et al. Cancers (Basel). 2024 Jun 28;16(13):2396. doi: 10.3390/cancers16132396. Cancers (Basel). 2024. PMID: 39001458 Free PMC article.
CONCLUSIONS: The validated Dutch translation showed high values for internal consistency, test-retest reliability, and validity, which allows us to implement the questionnaire in the early detection of LEL after gynecological cancer treatment....
CONCLUSIONS: The validated Dutch translation showed high values for internal consistency, test-retest reliability, and validity, which allow …