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Plasmid vaccination of stable HIV-positive subjects on antiviral treatment results in enhanced CD8 T-cell immunity and increased control of viral "blips".
Vaccine. 2005 Mar 18;23(17-18):2066-73. doi: 10.1016/j.vaccine.2005.01.010.
Vaccine. 2005.
PMID: 15755572
Clinical Trial.
First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: safety and host response.
MacGregor RR, Boyer JD, Ugen KE, Lacy KE, Gluckman SJ, Bagarazzi ML, Chattergoon MA, Baine Y, Higgins TJ, Ciccarelli RB, Coney LR, Ginsberg RS, Weiner DB.
MacGregor RR, et al.
J Infect Dis. 1998 Jul;178(1):92-100. doi: 10.1086/515613.
J Infect Dis. 1998.
PMID: 9652427
Clinical Trial.
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Evidence of active cytomegalovirus infection in clinically stable HIV-infected individuals with CD4+ lymphocyte counts below 100/microliters of blood: features and relation to risk of subsequent CMV retinitis.
MacGregor RR, Pakola SJ, Graziani AL, Montzka DP, Hodinka RL, Nichols CW, Friedman HM.
MacGregor RR, et al.
J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Nov 1;10(3):324-30.
J Acquir Immune Defic Syndr Hum Retrovirol. 1995.
PMID: 7552494
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