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34 results

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Page 1
Defining genome architecture at base-pair resolution.
Hua P, Badat M, Hanssen LLP, Hentges LD, Crump N, Downes DJ, Jeziorska DM, Oudelaar AM, Schwessinger R, Taylor S, Milne TA, Hughes JR, Higgs DR, Davies JOJ. Hua P, et al. Nature. 2021 Jul;595(7865):125-129. doi: 10.1038/s41586-021-03639-4. Epub 2021 Jun 9. Nature. 2021. PMID: 34108683
The MLL family of proteins in normal development and disease.
Milne TA. Milne TA. Biochim Biophys Acta Gene Regul Mech. 2020 Dec;1863(12):194648. doi: 10.1016/j.bbagrm.2020.194648. Epub 2020 Nov 4. Biochim Biophys Acta Gene Regul Mech. 2020. PMID: 33157274 No abstract available.
LEDGF: a leukemia-specific target.
Milne TA. Milne TA. Blood. 2018 Jan 4;131(1):4-5. doi: 10.1182/blood-2017-11-815449. Blood. 2018. PMID: 29301770 Free article. No abstract available.
MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia.
Crump NT, Smith AL, Godfrey L, Dopico-Fernandez AM, Denny N, Harman JR, Hamley JC, Jackson NE, Chahrour C, Riva S, Rice S, Kim J, Basrur V, Fermin D, Elenitoba-Johnson K, Roeder RG, Allis CD, Roberts I, Roy A, Geng H, Davies JOJ, Milne TA. Crump NT, et al. Nat Commun. 2023 Aug 25;14(1):5208. doi: 10.1038/s41467-023-40981-9. Nat Commun. 2023. PMID: 37626123 Free PMC article.
Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylation.
Park KC, Crump NT, Louwman N, Krywawych S, Cheong YJ, Vendrell I, Gill EK, Gunadasa-Rohling M, Ford KL, Hauton D, Fournier M, Pires E, Watson L, Roseman G, Holder J, Koschinski A, Carnicer R, Curtis MK, Zaccolo M, Hulikova A, Fischer R, Kramer HB, McCullagh JSO, Trefely S, Milne TA, Swietach P. Park KC, et al. Nat Cardiovasc Res. 2023 Dec;2(12):1221-1245. doi: 10.1038/s44161-023-00365-0. Epub 2023 Nov 23. Nat Cardiovasc Res. 2023. PMID: 38500966 Free PMC article.
Metabolic gatekeeper function of B-lymphoid transcription factors.
Chan LN, Chen Z, Braas D, Lee JW, Xiao G, Geng H, Cosgun KN, Hurtz C, Shojaee S, Cazzaniga V, Schjerven H, Ernst T, Hochhaus A, Kornblau SM, Konopleva M, Pufall MA, Cazzaniga G, Liu GJ, Milne TA, Koeffler HP, Ross TS, Sánchez-García I, Borkhardt A, Yamamoto KR, Dickins RA, Graeber TG, Müschen M. Chan LN, et al. Nature. 2017 Feb 23;542(7642):479-483. doi: 10.1038/nature21076. Epub 2017 Feb 13. Nature. 2017. PMID: 28192788 Free PMC article.
34 results