MH074411/MH/NIMH NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2007	4
2008	4
2009	5
2010	4
2011	4
2015	1
2024	0

1

Building a pharmacological lexicon: small molecule discovery in academia.

Lazo JS, Brady LS, Dingledine R. Lazo JS, et al. Mol Pharmacol. 2007 Jul;72(1):1-7. doi: 10.1124/mol.107.035113. Epub 2007 Apr 3. Mol Pharmacol. 2007. PMID: 17405872 Review.

2

Redox cycling compounds generate H2O2 in HTS buffers containing strong reducing reagents--real hits or promiscuous artifacts?

Johnston PA. Johnston PA. Curr Opin Chem Biol. 2011 Feb;15(1):174-82. doi: 10.1016/j.cbpa.2010.10.022. Epub 2010 Nov 11. Curr Opin Chem Biol. 2011. PMID: 21075044 Free PMC article. Review.

3

Synthesis and biological evaluation of 3-aminoisoquinolin-1(2H)-one based inhibitors of the dual-specificity phosphatase Cdc25B.

George Rosenker KM, Paquette WD, Johnston PA, Sharlow ER, Vogt A, Bakan A, Lazo JS, Wipf P. George Rosenker KM, et al. Bioorg Med Chem. 2015 Jun 15;23(12):2810-8. doi: 10.1016/j.bmc.2015.01.043. Epub 2015 Jan 31. Bioorg Med Chem. 2015. PMID: 25703307

4

Protein kinase D as a potential new target for cancer therapy.

LaValle CR, George KM, Sharlow ER, Lazo JS, Wipf P, Wang QJ. LaValle CR, et al. Biochim Biophys Acta. 2010 Dec;1806(2):183-92. doi: 10.1016/j.bbcan.2010.05.003. Epub 2010 May 24. Biochim Biophys Acta. 2010. PMID: 20580776 Free PMC article. Review.

5

Discovery of novel Myc-Max heterodimer disruptors with a three-dimensional pharmacophore model.

Mustata G, Follis AV, Hammoudeh DI, Metallo SJ, Wang H, Prochownik EV, Lazo JS, Bahar I. Mustata G, et al. J Med Chem. 2009 Mar 12;52(5):1247-50. doi: 10.1021/jm801278g. J Med Chem. 2009. PMID: 19215087 Free PMC article.

6

Toward a molecular understanding of the interaction of dual specificity phosphatases with substrates: insights from structure-based modeling and high throughput screening.

Bakan A, Lazo JS, Wipf P, Brummond KM, Bahar I. Bakan A, et al. Curr Med Chem. 2008;15(25):2536-44. doi: 10.2174/092986708785909003. Curr Med Chem. 2008. PMID: 18855677 Free PMC article. Review.

7

Data mining a small molecule drug screening representative subset from NIH PubChem.

Xie XQ, Chen JZ. Xie XQ, et al. J Chem Inf Model. 2008 Mar;48(3):465-75. doi: 10.1021/ci700193u. Epub 2008 Feb 27. J Chem Inf Model. 2008. PMID: 18302356

8

Design, Synthesis, and Biological Evaluation of PKD Inhibitors.

George KM, Frantz MC, Bravo-Altamirano K, Lavalle CR, Tandon M, Leimgruber S, Sharlow ER, Lazo JS, Wang QJ, Wipf P. George KM, et al. Pharmaceutics. 2011;3(2):186-228. doi: 10.3390/pharmaceutics3020186. Pharmaceutics. 2011. PMID: 22267986 Free PMC article.

9

Diverging Rh(I)-catalyzed carbocylization strategy to prepare a library of unique cyclic ethers.

Mao S, Probst D, Werner S, Chen J, Xie X, Brummond KM. Mao S, et al. J Comb Chem. 2008 Mar-Apr;10(2):235-46. doi: 10.1021/cc7001843. Epub 2008 Feb 14. J Comb Chem. 2008. PMID: 18271514

10

Profiling the NIH Small Molecule Repository for compounds that generate H2O2 by redox cycling in reducing environments.

Soares KM, Blackmon N, Shun TY, Shinde SN, Takyi HK, Wipf P, Lazo JS, Johnston PA. Soares KM, et al. Assay Drug Dev Technol. 2010 Apr;8(2):152-74. doi: 10.1089/adt.2009.0247. Assay Drug Dev Technol. 2010. PMID: 20070233 Free PMC article.

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