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Page 1
Plasma p-tau231: a new biomarker for incipient Alzheimer's disease pathology.
Ashton NJ, Pascoal TA, Karikari TK, Benedet AL, Lantero-Rodriguez J, Brinkmalm G, Snellman A, Schöll M, Troakes C, Hye A, Gauthier S, Vanmechelen E, Zetterberg H, Rosa-Neto P, Blennow K. Ashton NJ, et al. Acta Neuropathol. 2021 May;141(5):709-724. doi: 10.1007/s00401-021-02275-6. Epub 2021 Feb 14. Acta Neuropathol. 2021. PMID: 33585983 Free PMC article.
Microglial activation and tau propagate jointly across Braak stages.
Pascoal TA, Benedet AL, Ashton NJ, Kang MS, Therriault J, Chamoun M, Savard M, Lussier FZ, Tissot C, Karikari TK, Ottoy J, Mathotaarachchi S, Stevenson J, Massarweh G, Schöll M, de Leon MJ, Soucy JP, Edison P, Blennow K, Zetterberg H, Gauthier S, Rosa-Neto P. Pascoal TA, et al. Nat Med. 2021 Sep;27(9):1592-1599. doi: 10.1038/s41591-021-01456-w. Epub 2021 Aug 26. Nat Med. 2021. PMID: 34446931
Association of Phosphorylated Tau Biomarkers With Amyloid Positron Emission Tomography vs Tau Positron Emission Tomography.
Therriault J, Vermeiren M, Servaes S, Tissot C, Ashton NJ, Benedet AL, Karikari TK, Lantero-Rodriguez J, Brum WS, Lussier FZ, Bezgin G, Stevenson J, Rahmouni N, Kunach P, Wang YT, Fernandez-Arias J, Socualaya KQ, Macedo AC, Ferrari-Souza JP, Ferreira PCL, Bellaver B, Leffa DT, Zimmer ER, Vitali P, Soucy JP, Triana-Baltzer G, Kolb HC, Pascoal TA, Saha-Chaudhuri P, Gauthier S, Zetterberg H, Blennow K, Rosa-Neto P. Therriault J, et al. JAMA Neurol. 2023 Feb 1;80(2):188-199. doi: 10.1001/jamaneurol.2022.4485. JAMA Neurol. 2023. PMID: 36508198 Free PMC article.
Longitudinal 18F-MK-6240 tau tangles accumulation follows Braak stages.
Pascoal TA, Benedet AL, Tudorascu DL, Therriault J, Mathotaarachchi S, Savard M, Lussier FZ, Tissot C, Chamoun M, Kang MS, Stevenson J, Massarweh G, Guiot MC, Soucy JP, Gauthier S, Rosa-Neto P. Pascoal TA, et al. Brain. 2021 Dec 16;144(11):3517-3528. doi: 10.1093/brain/awab248. Brain. 2021. PMID: 34515754 Free PMC article.
[11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer's disease.
Pascoal TA, Chamoun M, Lax E, Wey HY, Shin M, Ng KP, Kang MS, Mathotaarachchi S, Benedet AL, Therriault J, Lussier FZ, Schroeder FA, DuBois JM, Hightower BG, Gilbert TM, Zürcher NR, Wang C, Hopewell R, Chakravarty M, Savard M, Thomas E, Mohaddes S, Farzin S, Salaciak A, Tullo S, Cuello AC, Soucy JP, Massarweh G, Hwang H, Kobayashi E, Hyman BT, Dickerson BC, Guiot MC, Szyf M, Gauthier S, Hooker JM, Rosa-Neto P. Pascoal TA, et al. Nat Commun. 2022 Jul 19;13(1):4171. doi: 10.1038/s41467-022-30653-5. Nat Commun. 2022. PMID: 35853847 Free PMC article.
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