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Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation.
Toussaint M, Jackson DJ, Swieboda D, Guedán A, Tsourouktsoglou TD, Ching YM, Radermecker C, Makrinioti H, Aniscenko J, Bartlett NW, Edwards MR, Solari R, Farnir F, Papayannopoulos V, Bureau F, Marichal T, Johnston SL. Toussaint M, et al. Nat Med. 2017 Jun;23(6):681-691. doi: 10.1038/nm.4332. Epub 2017 May 1. Nat Med. 2017. PMID: 28459437 Free PMC article.
Effect of CRTH2 antagonism on the response to experimental rhinovirus infection in asthma: a pilot randomised controlled trial.
Farne H, Glanville N, Johnson N, Kebadze T, Aniscenko J, Regis E, Zhu J, Trujillo-Torralbo MB, Kon OM, Mallia P, Prevost AT, Edwards MR, Johnston SL, Singanayagam A, Jackson DJ. Farne H, et al. Thorax. 2022 Oct;77(10):950-959. doi: 10.1136/thoraxjnl-2021-217429. Epub 2021 Oct 29. Thorax. 2022. PMID: 34716281 Free PMC article. Clinical Trial.