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A prenylated dsRNA sensor protects against severe COVID-19.
Wickenhagen A, Sugrue E, Lytras S, Kuchi S, Noerenberg M, Turnbull ML, Loney C, Herder V, Allan J, Jarmson I, Cameron-Ruiz N, Varjak M, Pinto RM, Lee JY, Iselin L, Palmalux N, Stewart DG, Swingler S, Greenwood EJD, Crozier TWM, Gu Q, Davies EL, Clohisey S, Wang B, Trindade Maranhão Costa F, Freire Santana M, de Lima Ferreira LC, Murphy L, Fawkes A, Meynert A, Grimes G; ISARIC4C Investigators; Da Silva Filho JL, Marti M, Hughes J, Stanton RJ, Wang ECY, Ho A, Davis I, Jarrett RF, Castello A, Robertson DL, Semple MG, Openshaw PJM, Palmarini M, Lehner PJ, Baillie JK, Rihn SJ, Wilson SJ. Wickenhagen A, et al. Science. 2021 Oct 29;374(6567):eabj3624. doi: 10.1126/science.abj3624. Epub 2021 Oct 29. Science. 2021. PMID: 34581622 Free PMC article.
HCMV-secreted glycoprotein gpUL4 inhibits TRAIL-mediated apoptosis and NK cell activation.
Vlachava VM, Seirafian S, Fielding CA, Kollnberger S, Aicheler RJ, Hughes J, Baker A, Weekes MP, Forbes S, Wilkinson GWG, Wang ECY, Stanton RJ. Vlachava VM, et al. Proc Natl Acad Sci U S A. 2023 Dec 5;120(49):e2309077120. doi: 10.1073/pnas.2309077120. Epub 2023 Nov 27. Proc Natl Acad Sci U S A. 2023. PMID: 38011551 Free PMC article.
Human cytomegalovirus protein pUL36: A dual cell death pathway inhibitor.
Fletcher-Etherington A, Nobre L, Nightingale K, Antrobus R, Nichols J, Davison AJ, Stanton RJ, Weekes MP. Fletcher-Etherington A, et al. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18771-18779. doi: 10.1073/pnas.2001887117. Epub 2020 Jul 20. Proc Natl Acad Sci U S A. 2020. PMID: 32690704 Free PMC article.
Differential cellular and humoral immune responses in immunocompromised individuals following multiple SARS-CoV-2 vaccinations.
Meredith RT, Bermingham MD, Bentley K, Agah S, Aboagye-Odei A, Yarham RAR, Mills H, Shaikh M, Hoye N, Stanton RJ, Chadwick DR, Oliver MA. Meredith RT, et al. Front Cell Infect Microbiol. 2023 Jun 23;13:1207313. doi: 10.3389/fcimb.2023.1207313. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37424787 Free PMC article.
40 results