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Chemically defined cytokine-free expansion of human haematopoietic stem cells.
Sakurai M, Ishitsuka K, Ito R, Wilkinson AC, Kimura T, Mizutani E, Nishikii H, Sudo K, Becker HJ, Takemoto H, Sano T, Kataoka K, Takahashi S, Nakamura Y, Kent DG, Iwama A, Chiba S, Okamoto S, Nakauchi H, Yamazaki S. Sakurai M, et al. Nature. 2023 Mar;615(7950):127-133. doi: 10.1038/s41586-023-05739-9. Epub 2023 Feb 22. Nature. 2023. PMID: 36813966 Free article.
Hematopoietic stem cells depend on HIM and HER.
Kent DG. Kent DG. Exp Hematol. 2022 Dec;116:15-17. doi: 10.1016/j.exphem.2022.10.004. Epub 2022 Oct 17. Exp Hematol. 2022. PMID: 36265671 Free article. Review.
Identification and characterization of in vitro expanded hematopoietic stem cells.
Che JLC, Bode D, Kucinski I, Cull AH, Bain F, Becker HJ, Jassinskaja M, Barile M, Boyd G, Belmonte M, Zeng AGX, Igarashi KJ, Rubio-Lara J, Shepherd MS, Clay A, Dick JE, Wilkinson AC, Nakauchi H, Yamazaki S, Göttgens B, Kent DG. Che JLC, et al. EMBO Rep. 2022 Oct 6;23(10):e55502. doi: 10.15252/embr.202255502. Epub 2022 Aug 16. EMBO Rep. 2022. PMID: 35971894 Free PMC article.
Preleukemic single-cell landscapes reveal mutation-specific mechanisms and gene programs predictive of AML patient outcomes.
Isobe T, Kucinski I, Barile M, Wang X, Hannah R, Bastos HP, Chabra S, Vijayabaskar MS, Sturgess KHM, Williams MJ, Giotopoulos G, Marando L, Li J, Rak J, Gozdecka M, Prins D, Shepherd MS, Watcham S, Green AR, Kent DG, Vassiliou GS, Huntly BJP, Wilson NK, Göttgens B. Isobe T, et al. Cell Genom. 2023 Oct 27;3(12):100426. doi: 10.1016/j.xgen.2023.100426. eCollection 2023 Dec 13. Cell Genom. 2023. PMID: 38116120 Free PMC article.
Exploiting Single-Cell Tools in Gene and Cell Therapy.
Bode D, Cull AH, Rubio-Lara JA, Kent DG. Bode D, et al. Front Immunol. 2021 Jul 12;12:702636. doi: 10.3389/fimmu.2021.702636. eCollection 2021. Front Immunol. 2021. PMID: 34322133 Free PMC article. Review.
11 results