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Glucose-6-phosphatase overexpression lowers glucose 6-phosphate and inhibits glycogen synthesis and glycolysis in hepatocytes without affecting glucokinase translocation. Evidence against feedback inhibition of glucokinase.
J Biol Chem. 1999 Aug 27;274(35):24559-66. doi: 10.1074/jbc.274.35.24559.
J Biol Chem. 1999.
PMID: 10455119
Free article.
Metabolic impact of adenovirus-mediated overexpression of the glucose-6-phosphatase catalytic subunit in hepatocytes.
Seoane J, Trinh K, O'Doherty RM, Gómez-Foix AM, Lange AJ, Newgard CB, Guinovart JJ.
Seoane J, et al.
J Biol Chem. 1997 Oct 24;272(43):26972-7. doi: 10.1074/jbc.272.43.26972.
J Biol Chem. 1997.
PMID: 9341134
Free article.
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