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Cellular thermal shift assay for the identification of drug-target interactions in the Plasmodium falciparum proteome.
Nat Protoc. 2020 Jun;15(6):1881-1921. doi: 10.1038/s41596-020-0310-z. Epub 2020 Apr 27.
Nat Protoc. 2020.
PMID: 32341577
Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initial transcriptional response.
Zhu L, van der Pluijm RW, Kucharski M, Nayak S, Tripathi J, White NJ, Day NPJ, Faiz A, Phyo AP, Amaratunga C, Lek D, Ashley EA, Nosten F, Smithuis F, Ginsburg H, von Seidlein L, Lin K, Imwong M, Chotivanich K, Mayxay M, Dhorda M, Nguyen HC, Nguyen TNT, Miotto O, Newton PN, Jittamala P, Tripura R, Pukrittayakamee S, Peto TJ, Hien TT, Dondorp AM, Bozdech Z.
Zhu L, et al.
Commun Biol. 2022 Mar 28;5(1):274. doi: 10.1038/s42003-022-03215-0.
Commun Biol. 2022.
PMID: 35347215
Free PMC article.
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