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Antiviral CD4+ memory T cells are IL-15 dependent.
Purton JF, Tan JT, Rubinstein MP, Kim DM, Sprent J, Surh CD. Purton JF, et al. J Exp Med. 2007 Apr 16;204(4):951-61. doi: 10.1084/jem.20061805. Epub 2007 Apr 9. J Exp Med. 2007. PMID: 17420265 Free PMC article.
Converting IL-15 to a superagonist by binding to soluble IL-15R{alpha}.
Rubinstein MP, Kovar M, Purton JF, Cho JH, Boyman O, Surh CD, Sprent J. Rubinstein MP, et al. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9166-71. doi: 10.1073/pnas.0600240103. Epub 2006 Jun 6. Proc Natl Acad Sci U S A. 2006. PMID: 16757567 Free PMC article.
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