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Page 1
γ-Secretase inhibitors and modulators.
Golde TE, Koo EH, Felsenstein KM, Osborne BA, Miele L. Golde TE, et al. Biochim Biophys Acta. 2013 Dec;1828(12):2898-907. doi: 10.1016/j.bbamem.2013.06.005. Epub 2013 Jun 17. Biochim Biophys Acta. 2013. PMID: 23791707 Free PMC article. Review.
Notch inhibitors for cancer treatment.
Espinoza I, Miele L. Espinoza I, et al. Pharmacol Ther. 2013 Aug;139(2):95-110. doi: 10.1016/j.pharmthera.2013.02.003. Epub 2013 Feb 28. Pharmacol Ther. 2013. PMID: 23458608 Free PMC article. Review.
Targeting Notch to target cancer stem cells.
Pannuti A, Foreman K, Rizzo P, Osipo C, Golde T, Osborne B, Miele L. Pannuti A, et al. Clin Cancer Res. 2010 Jun 15;16(12):3141-52. doi: 10.1158/1078-0432.CCR-09-2823. Epub 2010 Jun 8. Clin Cancer Res. 2010. PMID: 20530696 Free PMC article. Review.
BRI2 (ITM2b) inhibits Abeta deposition in vivo.
Kim J, Miller VM, Levites Y, West KJ, Zwizinski CW, Moore BD, Troendle FJ, Bann M, Verbeeck C, Price RW, Smithson L, Sonoda L, Wagg K, Rangachari V, Zou F, Younkin SG, Graff-Radford N, Dickson D, Rosenberry T, Golde TE. Kim J, et al. J Neurosci. 2008 Jun 4;28(23):6030-6. doi: 10.1523/JNEUROSCI.0891-08.2008. J Neurosci. 2008. PMID: 18524908 Free PMC article.
Notch signaling regulates mouse and human Th17 differentiation.
Keerthivasan S, Suleiman R, Lawlor R, Roderick J, Bates T, Minter L, Anguita J, Juncadella I, Nickoloff BJ, Le Poole IC, Miele L, Osborne BA. Keerthivasan S, et al. J Immunol. 2011 Jul 15;187(2):692-701. doi: 10.4049/jimmunol.1003658. Epub 2011 Jun 17. J Immunol. 2011. PMID: 21685328 Free PMC article.
26 results