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Page 1
SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2.
Clausen TM, Sandoval DR, Spliid CB, Pihl J, Perrett HR, Painter CD, Narayanan A, Majowicz SA, Kwong EM, McVicar RN, Thacker BE, Glass CA, Yang Z, Torres JL, Golden GJ, Bartels PL, Porell RN, Garretson AF, Laubach L, Feldman J, Yin X, Pu Y, Hauser BM, Caradonna TM, Kellman BP, Martino C, Gordts PLSM, Chanda SK, Schmidt AG, Godula K, Leibel SL, Jose J, Corbett KD, Ward AB, Carlin AF, Esko JD. Clausen TM, et al. Cell. 2020 Nov 12;183(4):1043-1057.e15. doi: 10.1016/j.cell.2020.09.033. Epub 2020 Sep 14. Cell. 2020. PMID: 32970989 Free PMC article.
Spike-heparan sulfate interactions in SARS-CoV-2 infection.
Kearns FL, Sandoval DR, Casalino L, Clausen TM, Rosenfeld MA, Spliid CB, Amaro RE, Esko JD. Kearns FL, et al. Curr Opin Struct Biol. 2022 Oct;76:102439. doi: 10.1016/j.sbi.2022.102439. Epub 2022 Jul 6. Curr Opin Struct Biol. 2022. PMID: 35926454 Free PMC article. Review.
SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling.
Biering SB, Gomes de Sousa FT, Tjang LV, Pahmeier F, Zhu C, Ruan R, Blanc SF, Patel TS, Worthington CM, Glasner DR, Castillo-Rojas B, Servellita V, Lo NTN, Wong MP, Warnes CM, Sandoval DR, Clausen TM, Santos YA, Fox DM, Ortega V, Näär AM, Baric RS, Stanley SA, Aguilar HC, Esko JD, Chiu CY, Pak JE, Beatty PR, Harris E. Biering SB, et al. Nat Commun. 2022 Dec 9;13(1):7630. doi: 10.1038/s41467-022-34910-5. Nat Commun. 2022. PMID: 36494335 Free PMC article.
A Systems View of the Heparan Sulfate Interactome.
Gómez Toledo A, Sorrentino JT, Sandoval DR, Malmström J, Lewis NE, Esko JD. Gómez Toledo A, et al. J Histochem Cytochem. 2021 Feb;69(2):105-119. doi: 10.1369/0022155420988661. J Histochem Cytochem. 2021. PMID: 33494649 Free PMC article. Review.
Neuronal Ndst1 depletion accelerates prion protein clearance and slows neurodegeneration in prion infection.
Aguilar-Calvo P, Malik A, Sandoval DR, Barback C, Orrù CD, Standke HG, Thomas OR, Dwyer CA, Pizzo DP, Bapat J, Soldau K, Ogawa R, Riley MB, Nilsson KPR, Kraus A, Caughey B, Iliff JJ, Vera DR, Esko JD, Sigurdson CJ. Aguilar-Calvo P, et al. PLoS Pathog. 2023 Sep 25;19(9):e1011487. doi: 10.1371/journal.ppat.1011487. eCollection 2023 Sep. PLoS Pathog. 2023. PMID: 37747931 Free PMC article.
CCR3-dependent eosinophil recruitment is regulated by sialyltransferase ST3Gal-IV.
Immler R, Nussbaumer K, Doerner A, El Bounkari O, Huber S, Abisch J, Napoli M, Schmidt S, Margraf A, Pruenster M, Rohwedder I, Lange-Sperandio B, Mall MA, de Jong R, Ohnmacht C, Bernhagen J, Voehringer D, Marth JD, Frommhold D, Sperandio M. Immler R, et al. Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2319057121. doi: 10.1073/pnas.2319057121. Epub 2024 Apr 30. Proc Natl Acad Sci U S A. 2024. PMID: 38687790 Free PMC article.
Elongated neutrophil-derived structures are blood-borne microparticles formed by rolling neutrophils during sepsis.
Marki A, Buscher K, Lorenzini C, Meyer M, Saigusa R, Fan Z, Yeh YT, Hartmann N, Dan JM, Kiosses WB, Golden GJ, Ganesan R, Winkels H, Orecchioni M, McArdle S, Mikulski Z, Altman Y, Bui J, Kronenberg M, Chien S, Esko JD, Nizet V, Smalley D, Roth J, Ley K. Marki A, et al. J Exp Med. 2021 Mar 1;218(3):e20200551. doi: 10.1084/jem.20200551. J Exp Med. 2021. PMID: 33275138 Free PMC article.
45 results