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Aging and neurodegeneration are associated with increased mutations in single human neurons.
Lodato MA, Rodin RE, Bohrson CL, Coulter ME, Barton AR, Kwon M, Sherman MA, Vitzthum CM, Luquette LJ, Yandava CN, Yang P, Chittenden TW, Hatem NE, Ryu SC, Woodworth MB, Park PJ, Walsh CA. Lodato MA, et al. Science. 2018 Feb 2;359(6375):555-559. doi: 10.1126/science.aao4426. Epub 2017 Dec 7. Science. 2018. PMID: 29217584 Free PMC article.
Activity-dependent regulome of human GABAergic neurons reveals new patterns of gene regulation and neurological disease heritability.
Boulting GL, Durresi E, Ataman B, Sherman MA, Mei K, Harmin DA, Carter AC, Hochbaum DR, Granger AJ, Engreitz JM, Hrvatin S, Blanchard MR, Yang MG, Griffith EC, Greenberg ME. Boulting GL, et al. Nat Neurosci. 2021 Mar;24(3):437-448. doi: 10.1038/s41593-020-00786-1. Epub 2021 Feb 4. Nat Neurosci. 2021. PMID: 33542524 Free PMC article.
Deep Learning Benchmarks on L1000 Gene Expression Data.
McDermott MBA, Wang J, Zhao WN, Sheridan SD, Szolovits P, Kohane I, Haggarty SJ, Perlis RH. McDermott MBA, et al. IEEE/ACM Trans Comput Biol Bioinform. 2020 Nov-Dec;17(6):1846-1857. doi: 10.1109/TCBB.2019.2910061. Epub 2020 Dec 8. IEEE/ACM Trans Comput Biol Bioinform. 2020. PMID: 30990190 Free PMC article.
76 results