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Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease.
Barbier-Torres L, Murray B, Yang JW, Wang J, Matsuda M, Robinson A, Binek A, Fan W, Fernández-Ramos D, Lopitz-Otsoa F, Luque-Urbano M, Millet O, Mavila N, Peng H, Ramani K, Gottlieb R, Sun Z, Liangpunsakul S, Seki E, Van Eyk JE, Mato JM, Lu SC. Barbier-Torres L, et al. Nat Commun. 2022 Jan 28;13(1):557. doi: 10.1038/s41467-022-28201-2. Nat Commun. 2022. PMID: 35091576 Free PMC article.
Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22.
Wang Q, Kim SY, Matsushita H, Wang Z, Pandyarajan V, Matsuda M, Ohashi K, Tsuchiya T, Roh YS, Kiani C, Zhao Y, Chan M, Devkota S, Lu SC, Hayashi T, Carson DA, Seki E. Wang Q, et al. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2020868118. doi: 10.1073/pnas.2020868118. Epub 2020 Dec 21. Proc Natl Acad Sci U S A. 2021. PMID: 33443222 Free PMC article.