R01 AG019787/AG/NIA NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2002	1
2003	1
2005	1
2006	1
2007	2
2008	4
2009	4
2010	4
2011	1
2012	1
2014	1
2016	2
2024	0

1

Amelioration of premature aging in mtDNA mutator mouse by exercise: the interplay of oxidative stress, PGC-1α, p53, and DNA damage. A hypothesis.

Safdar A, Annis S, Kraytsberg Y, Laverack C, Saleem A, Popadin K, Woods DC, Tilly JL, Khrapko K. Safdar A, et al. Curr Opin Genet Dev. 2016 Jun;38:127-132. doi: 10.1016/j.gde.2016.06.011. Epub 2016 Aug 3. Curr Opin Genet Dev. 2016. PMID: 27497229 Free PMC article. Review.

2

Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice.

Safdar A, Khrapko K, Flynn JM, Saleem A, De Lisio M, Johnston AP, Kratysberg Y, Samjoo IA, Kitaoka Y, Ogborn DI, Little JP, Raha S, Parise G, Akhtar M, Hettinga BP, Rowe GC, Arany Z, Prolla TA, Tarnopolsky MA. Safdar A, et al. Skelet Muscle. 2016 Jan 31;6:7. doi: 10.1186/s13395-016-0075-9. eCollection 2016. Skelet Muscle. 2016. Retraction in: Skelet Muscle. 2021 Mar 30;11(1):8. doi: 10.1186/s13395-021-00264-7 PMID: 26834962 Free PMC article. Retracted.

3

Mitochondrial DNA mutations and aging: devils in the details?

Khrapko K, Vijg J. Khrapko K, et al. Trends Genet. 2009 Feb;25(2):91-8. doi: 10.1016/j.tig.2008.11.007. Epub 2008 Dec 26. Trends Genet. 2009. PMID: 19110336 Free PMC article. Review.

4

Quantification of mitochondrial DNA mutation load.

Greaves LC, Beadle NE, Taylor GA, Commane D, Mathers JC, Khrapko K, Turnbull DM. Greaves LC, et al. Aging Cell. 2009 Sep;8(5):566-72. doi: 10.1111/j.1474-9726.2009.00505.x. Epub 2009 Jul 18. Aging Cell. 2009. PMID: 19624578 Free PMC article.

5

The timing of mitochondrial DNA mutations in aging.

Khrapko K. Khrapko K. Nat Genet. 2011 Jul 27;43(8):726-7. doi: 10.1038/ng.895. Nat Genet. 2011. PMID: 21792237 Free PMC article.

6

Two ways to make an mtDNA bottleneck.

Khrapko K. Khrapko K. Nat Genet. 2008 Feb;40(2):134-5. doi: 10.1038/ng0208-134. Nat Genet. 2008. PMID: 18227871 Free PMC article.

7

Analysis of mutational spectra by denaturing capillary electrophoresis.

Ekstrøm PO, Khrapko K, Li-Sucholeiki XC, Hunter IW, Thilly WG. Ekstrøm PO, et al. Nat Protoc. 2008;3(7):1153-66. doi: 10.1038/nprot.2008.79. Nat Protoc. 2008. PMID: 18600220 Free PMC article.

8

The complexity of aging: are some aging processes more equal than others?

Khrapko K. Khrapko K. Mech Ageing Dev. 2007 Jul-Aug;128(7-8):463-5. doi: 10.1016/j.mad.2007.05.003. Epub 2007 May 21. Mech Ageing Dev. 2007. PMID: 17604082 Free PMC article. Review.

9

Recombination of mitochondrial DNA in skeletal muscle of individuals with multiple mitochondrial DNA heteroplasmy.

Zsurka G, Kraytsberg Y, Kudina T, Kornblum C, Elger CE, Khrapko K, Kunz WS. Zsurka G, et al. Nat Genet. 2005 Aug;37(8):873-7. doi: 10.1038/ng1606. Epub 2005 Jul 17. Nat Genet. 2005. PMID: 16025113 Free PMC article.

10

Inheritance of mitochondrial DNA recombinants in double-heteroplasmic families: potential implications for phylogenetic analysis.

Zsurka G, Hampel KG, Kudina T, Kornblum C, Kraytsberg Y, Elger CE, Khrapko K, Kunz WS. Zsurka G, et al. Am J Hum Genet. 2007 Feb;80(2):298-305. doi: 10.1086/511282. Epub 2006 Dec 27. Am J Hum Genet. 2007. PMID: 17236134 Free PMC article.

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