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Page 1
Biomarkers of aging for the identification and evaluation of longevity interventions.
Moqri M, Herzog C, Poganik JR; Biomarkers of Aging Consortium; Justice J, Belsky DW, Higgins-Chen A, Moskalev A, Fuellen G, Cohen AA, Bautmans I, Widschwendter M, Ding J, Fleming A, Mannick J, Han JJ, Zhavoronkov A, Barzilai N, Kaeberlein M, Cummings S, Kennedy BK, Ferrucci L, Horvath S, Verdin E, Maier AB, Snyder MP, Sebastiano V, Gladyshev VN. Moqri M, et al. Cell. 2023 Aug 31;186(18):3758-3775. doi: 10.1016/j.cell.2023.08.003. Cell. 2023. PMID: 37657418 Free PMC article. Review.
Loss of epigenetic information as a cause of mammalian aging.
Yang JH, Hayano M, Griffin PT, Amorim JA, Bonkowski MS, Apostolides JK, Salfati EL, Blanchette M, Munding EM, Bhakta M, Chew YC, Guo W, Yang X, Maybury-Lewis S, Tian X, Ross JM, Coppotelli G, Meer MV, Rogers-Hammond R, Vera DL, Lu YR, Pippin JW, Creswell ML, Dou Z, Xu C, Mitchell SJ, Das A, O'Connell BL, Thakur S, Kane AE, Su Q, Mohri Y, Nishimura EK, Schaevitz L, Garg N, Balta AM, Rego MA, Gregory-Ksander M, Jakobs TC, Zhong L, Wakimoto H, El Andari J, Grimm D, Mostoslavsky R, Wagers AJ, Tsubota K, Bonasera SJ, Palmeira CM, Seidman JG, Seidman CE, Wolf NS, Kreiling JA, Sedivy JM, Murphy GF, Green RE, Garcia BA, Berger SL, Oberdoerffer P, Shankland SJ, Gladyshev VN, Ksander BR, Pfenning AR, Rajman LA, Sinclair DA. Yang JH, et al. Cell. 2023 Jan 19;186(2):305-326.e27. doi: 10.1016/j.cell.2022.12.027. Epub 2023 Jan 12. Cell. 2023. PMID: 36638792 Free PMC article.
Validation of biomarkers of aging.
Moqri M, Herzog C, Poganik JR, Ying K, Justice JN, Belsky DW, Higgins-Chen AT, Chen BH, Cohen AA, Fuellen G, Hägg S, Marioni RE, Widschwendter M, Fortney K, Fedichev PO, Zhavoronkov A, Barzilai N, Lasky-Su J, Kiel DP, Kennedy BK, Cummings S, Slagboom PE, Verdin E, Maier AB, Sebastiano V, Snyder MP, Gladyshev VN, Horvath S, Ferrucci L. Moqri M, et al. Nat Med. 2024 Feb;30(2):360-372. doi: 10.1038/s41591-023-02784-9. Epub 2024 Feb 14. Nat Med. 2024. PMID: 38355974 Free PMC article. Review.
Causality-enriched epigenetic age uncouples damage and adaptation.
Ying K, Liu H, Tarkhov AE, Sadler MC, Lu AT, Moqri M, Horvath S, Kutalik Z, Shen X, Gladyshev VN. Ying K, et al. Nat Aging. 2024 Feb;4(2):231-246. doi: 10.1038/s43587-023-00557-0. Epub 2024 Jan 19. Nat Aging. 2024. PMID: 38243142 Free PMC article.
Biological age is increased by stress and restored upon recovery.
Poganik JR, Zhang B, Baht GS, Tyshkovskiy A, Deik A, Kerepesi C, Yim SH, Lu AT, Haghani A, Gong T, Hedman AM, Andolf E, Pershagen G, Almqvist C, Clish CB, Horvath S, White JP, Gladyshev VN. Poganik JR, et al. Cell Metab. 2023 May 2;35(5):807-820.e5. doi: 10.1016/j.cmet.2023.03.015. Epub 2023 Apr 21. Cell Metab. 2023. PMID: 37086720 Free PMC article.
Metabolism, homeostasis, and aging.
Moldakozhayev A, Gladyshev VN. Moldakozhayev A, et al. Trends Endocrinol Metab. 2023 Mar;34(3):158-169. doi: 10.1016/j.tem.2023.01.003. Epub 2023 Jan 20. Trends Endocrinol Metab. 2023. PMID: 36681595 Free PMC article. Review.
Profiling epigenetic age in single cells.
Trapp A, Kerepesi C, Gladyshev VN. Trapp A, et al. Nat Aging. 2021 Dec;1(12):1189-1201. doi: 10.1038/s43587-021-00134-3. Epub 2021 Dec 9. Nat Aging. 2021. PMID: 36211119 Free PMC article.
Molecular Damage in Aging.
Gladyshev VN, Kritchevsky SB, Clarke SG, Cuervo AM, Fiehn O, de Magalhães JP, Mau T, Maes M, Moritz R, Niedernhofer LJ, Van Schaftingen E, Tranah GJ, Walsh K, Yura Y, Zhang B, Cummings SR. Gladyshev VN, et al. Nat Aging. 2021 Dec;1(12):1096-1106. doi: 10.1038/s43587-021-00150-3. Epub 2021 Dec 20. Nat Aging. 2021. PMID: 36846190 Free PMC article. Review.
24 results