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Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain.
Rayaprolu S, Bitarafan S, Santiago JV, Betarbet R, Sunna S, Cheng L, Xiao H, Nelson RS, Kumar P, Bagchi P, Duong DM, Goettemoeller AM, Oláh VJ, Rowan M, Levey AI, Wood LB, Seyfried NT, Rangaraju S. Rayaprolu S, et al. Nat Commun. 2022 May 25;13(1):2927. doi: 10.1038/s41467-022-30623-x. Nat Commun. 2022. PMID: 35614064 Free PMC article.
APOE expression and secretion are modulated by mitochondrial dysfunction.
Wynne ME, Ogunbona O, Lane AR, Gokhale A, Zlatic SA, Xu C, Wen Z, Duong DM, Rayaprolu S, Ivanova A, Ortlund EA, Dammer EB, Seyfried NT, Roberts BR, Crocker A, Shanbhag V, Petris M, Senoo N, Kandasamy S, Claypool SM, Barrientos A, Wingo A, Wingo TS, Rangaraju S, Levey AI, Werner E, Faundez V. Wynne ME, et al. Elife. 2023 May 12;12:e85779. doi: 10.7554/eLife.85779. Elife. 2023. PMID: 37171075 Free PMC article.
Native-state proteomics of Parvalbumin interneurons identifies unique molecular signatures and vulnerabilities to early Alzheimer's pathology.
Kumar P, Goettemoeller AM, Espinosa-Garcia C, Tobin BR, Tfaily A, Nelson RS, Natu A, Dammer EB, Santiago JV, Malepati S, Cheng L, Xiao H, Duong DD, Seyfried NT, Wood LB, Rowan MJM, Rangaraju S. Kumar P, et al. Nat Commun. 2024 Apr 1;15(1):2823. doi: 10.1038/s41467-024-47028-7. Nat Commun. 2024. PMID: 38561349 Free PMC article.
Integrative proteomics identifies a conserved Aβ amyloid responsome, novel plaque proteins, and pathology modifiers in Alzheimer's disease.
Levites Y, Dammer EB, Ran Y, Tsering W, Duong D, Abreha M, Gadhavi J, Lolo K, Trejo-Lopez J, Phillips J, Iturbe A, Erquizi A, Moore BD, Ryu D, Natu A, Dillon K, Torrellas J, Moran C, Ladd T, Afroz F, Islam T, Jagirdar J, Funk CC, Robinson M, Rangaraju S, Borchelt DR, Ertekin-Taner N, Kelly JW, Heppner FL, Johnson ECB, McFarland K, Levey AI, Prokop S, Seyfried NT, Golde TE. Levites Y, et al. Cell Rep Med. 2024 Aug 20;5(8):101669. doi: 10.1016/j.xcrm.2024.101669. Epub 2024 Aug 9. Cell Rep Med. 2024. PMID: 39127040 Free PMC article.
Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology.
Goettemoeller AM, Banks E, McCann KE, Kumar P, South K, Olah VJ, Ramelow CC, Duong DM, Seyfried NT, Rangaraju S, Weinshenker D, Rowan MJ. Goettemoeller AM, et al. Res Sq [Preprint]. 2023 Nov 6:rs.3.rs-3370607. doi: 10.21203/rs.3.rs-3370607/v1. Res Sq. 2023. Update in: Nat Commun. 2024 Sep 10;15(1):7918. doi: 10.1038/s41467-024-52297-3 PMID: 37987015 Free PMC article. Updated. Preprint.
18 results