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2011 7
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Cysteine Cathepsin Inhibitors as Anti-Ebola Agents.
van der Linden WA, Schulze CJ, Herbert AS, Krause TB, Wirchnianski AA, Dye JM, Chandran K, Bogyo M. van der Linden WA, et al. ACS Infect Dis. 2016 Mar 11;2(3):173-179. doi: 10.1021/acsinfecdis.5b00130. Epub 2016 Jan 20. ACS Infect Dis. 2016. PMID: 27347558 Free PMC article.
Filovirus entry into cells - new insights.
Miller EH, Chandran K. Miller EH, et al. Curr Opin Virol. 2012 Apr;2(2):206-14. doi: 10.1016/j.coviro.2012.02.015. Epub 2012 Mar 23. Curr Opin Virol. 2012. PMID: 22445965 Free PMC article. Review.
Ebola virus entry requires the cholesterol transporter Niemann-Pick C1.
Carette JE, Raaben M, Wong AC, Herbert AS, Obernosterer G, Mulherkar N, Kuehne AI, Kranzusch PJ, Griffin AM, Ruthel G, Dal Cin P, Dye JM, Whelan SP, Chandran K, Brummelkamp TR. Carette JE, et al. Nature. 2011 Aug 24;477(7364):340-3. doi: 10.1038/nature10348. Nature. 2011. PMID: 21866103 Free PMC article.
Structural basis for differential neutralization of ebolaviruses.
Bale S, Dias JM, Fusco ML, Hashiguchi T, Wong AC, Liu T, Keuhne AI, Li S, Woods VL Jr, Chandran K, Dye JM, Saphire EO. Bale S, et al. Viruses. 2012 Apr;4(4):447-70. doi: 10.3390/v4040447. Epub 2012 Apr 5. Viruses. 2012. PMID: 22590681 Free PMC article. Review.
A "Trojan horse" bispecific-antibody strategy for broad protection against ebolaviruses.
Wec AZ, Nyakatura EK, Herbert AS, Howell KA, Holtsberg FW, Bakken RR, Mittler E, Christin JR, Shulenin S, Jangra RK, Bharrhan S, Kuehne AI, Bornholdt ZA, Flyak AI, Saphire EO, Crowe JE Jr, Aman MJ, Dye JM, Lai JR, Chandran K. Wec AZ, et al. Science. 2016 Oct 21;354(6310):350-354. doi: 10.1126/science.aag3267. Epub 2016 Sep 8. Science. 2016. PMID: 27608667 Free PMC article.
A shared structural solution for neutralizing ebolaviruses.
Dias JM, Kuehne AI, Abelson DM, Bale S, Wong AC, Halfmann P, Muhammad MA, Fusco ML, Zak SE, Kang E, Kawaoka Y, Chandran K, Dye JM, Saphire EO. Dias JM, et al. Nat Struct Mol Biol. 2011 Nov 20;18(12):1424-7. doi: 10.1038/nsmb.2150. Nat Struct Mol Biol. 2011. PMID: 22101933 Free PMC article.
32 results