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Page 1
Clonal haematopoiesis and risk of chronic liver disease.
Wong WJ, Emdin C, Bick AG, Zekavat SM, Niroula A, Pirruccello JP, Dichtel L, Griffin G, Uddin MM, Gibson CJ, Kovalcik V, Lin AE, McConkey ME, Vromman A, Sellar RS, Kim PG, Agrawal M, Weinstock J, Long MT, Yu B, Banerjee R, Nicholls RC, Dennis A, Kelly M, Loh PR, McCarroll S, Boerwinkle E, Vasan RS, Jaiswal S, Johnson AD, Chung RT, Corey K, Levy D, Ballantyne C; NHLBI TOPMed Hematology Working Group; Ebert BL, Natarajan P. Wong WJ, et al. Nature. 2023 Apr;616(7958):747-754. doi: 10.1038/s41586-023-05857-4. Epub 2023 Apr 12. Nature. 2023. PMID: 37046084 Free PMC article.
Macrophage MerTK Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis.
Cai B, Dongiovanni P, Corey KE, Wang X, Shmarakov IO, Zheng Z, Kasikara C, Davra V, Meroni M, Chung RT, Rothlin CV, Schwabe RF, Blaner WS, Birge RB, Valenti L, Tabas I. Cai B, et al. Cell Metab. 2020 Feb 4;31(2):406-421.e7. doi: 10.1016/j.cmet.2019.11.013. Epub 2019 Dec 12. Cell Metab. 2020. PMID: 31839486 Free PMC article.
Epigenetic scars of CD8+ T cell exhaustion persist after cure of chronic infection in humans.
Yates KB, Tonnerre P, Martin GE, Gerdemann U, Al Abosy R, Comstock DE, Weiss SA, Wolski D, Tully DC, Chung RT, Allen TM, Kim AY, Fidler S, Fox J, Frater J, Lauer GM, Haining WN, Sen DR. Yates KB, et al. Nat Immunol. 2021 Aug;22(8):1020-1029. doi: 10.1038/s41590-021-00979-1. Epub 2021 Jul 26. Nat Immunol. 2021. PMID: 34312547 Free PMC article. Clinical Trial.
Peroxidasin Deficiency Re-programs Macrophages Toward Pro-fibrolysis Function and Promotes Collagen Resolution in Liver.
Sojoodi M, Erstad DJ, Barrett SC, Salloum S, Zhu S, Qian T, Colon S, Gale EM, Jordan VC, Wang Y, Li S, Ataeinia B, Jalilifiroozinezhad S, Lanuti M, Zukerberg L, Caravan P, Hoshida Y, Chung RT, Bhave G, Lauer GM, Fuchs BC, Tanabe KK. Sojoodi M, et al. Cell Mol Gastroenterol Hepatol. 2022;13(5):1483-1509. doi: 10.1016/j.jcmgh.2022.01.015. Epub 2022 Jan 28. Cell Mol Gastroenterol Hepatol. 2022. PMID: 35093588 Free PMC article.
Fatty Acids Activate the Transcriptional Coactivator YAP1 to Promote Liver Fibrosis via p38 Mitogen-Activated Protein Kinase.
Salloum S, Jeyarajan AJ, Kruger AJ, Holmes JA, Shao T, Sojoodi M, Kim MH, Zhuo Z, Shroff SG, Kassa A, Corey KE, Khan SK, Lin W, Alatrakchi N, Schaefer EAK, Chung RT. Salloum S, et al. Cell Mol Gastroenterol Hepatol. 2021;12(4):1297-1310. doi: 10.1016/j.jcmgh.2021.06.003. Epub 2021 Jun 9. Cell Mol Gastroenterol Hepatol. 2021. PMID: 34118488 Free PMC article.
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