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Differences underlying EGFR and HER2 oncogene addiction.
Faber AC, Wong KK, Engelman JA. Faber AC, et al. Cell Cycle. 2010 Mar 1;9(5):851-2. doi: 10.4161/cc.9.5.11096. Epub 2010 Mar 30. Cell Cycle. 2010. PMID: 20160489 Free PMC article. No abstract available.
An ErbB3 antibody, MM-121, is active in cancers with ligand-dependent activation.
Schoeberl B, Faber AC, Li D, Liang MC, Crosby K, Onsum M, Burenkova O, Pace E, Walton Z, Nie L, Fulgham A, Song Y, Nielsen UB, Engelman JA, Wong KK. Schoeberl B, et al. Cancer Res. 2010 Mar 15;70(6):2485-94. doi: 10.1158/0008-5472.CAN-09-3145. Epub 2010 Mar 9. Cancer Res. 2010. PMID: 20215504 Free PMC article.