R01 CA167677/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2012	6
2013	3
2014	4
2015	6
2016	3
2017	8
2018	6
2019	2
2021	1
2024	0

1

Function and regulation of tau conformations in the development and treatment of traumatic brain injury and neurodegeneration.

Albayram O, Herbert MK, Kondo A, Tsai CY, Baxley S, Lian X, Hansen M, Zhou XZ, Lu KP. Albayram O, et al. Cell Biosci. 2016 Dec 5;6:59. doi: 10.1186/s13578-016-0124-4. eCollection 2016. Cell Biosci. 2016. PMID: 27980715 Free PMC article. Review.

2

The Pin1-CaMKII-AMPA Receptor Axis Regulates Epileptic Susceptibility.

Hou X, Yang F, Li A, Zhao D, Ma N, Chen L, Lin S, Lin Y, Wang L, Yan X, Zheng M, Lee TH, Zhou XZ, Lu KP, Liu H. Hou X, et al. Cereb Cortex. 2021 May 10;31(6):3082-3095. doi: 10.1093/cercor/bhab004. Cereb Cortex. 2021. PMID: 33569579 Free PMC article.

3

Pin1-Targeted Therapy for Systemic Lupus Erythematosus.

Wei S, Yoshida N, Finn G, Kozono S, Nechama M, Kyttaris VC, Zhen Zhou X, Tsokos GC, Ping Lu K. Wei S, et al. Arthritis Rheumatol. 2016 Oct;68(10):2503-13. doi: 10.1002/art.39741. Arthritis Rheumatol. 2016. PMID: 27159270 Free PMC article.

4

Targeting Prion-like Cis Phosphorylated Tau Pathology in Neurodegenerative Diseases.

Albayram O, Angeli P, Bernstein E, Baxley S, Gao Z, Lu KP, Zhou XZ. Albayram O, et al. J Alzheimers Dis Parkinsonism. 2018;8(3):443. doi: 10.4172/2161-0460.1000443. Epub 2018 Jun 29. J Alzheimers Dis Parkinsonism. 2018. PMID: 30197831 Free PMC article.

5

Pin1 dysregulation helps to explain the inverse association between cancer and Alzheimer's disease.

Driver JA, Zhou XZ, Lu KP. Driver JA, et al. Biochim Biophys Acta. 2015 Oct;1850(10):2069-76. doi: 10.1016/j.bbagen.2014.12.025. Epub 2015 Jan 10. Biochim Biophys Acta. 2015. PMID: 25583562 Free PMC article. Review.

6

Regulation of phosphatidylinositol-5-phosphate signaling by Pin1 determines sensitivity to oxidative stress.

Keune WJ, Jones DR, Bultsma Y, Sommer L, Zhou XZ, Lu KP, Divecha N. Keune WJ, et al. Sci Signal. 2012 Nov 27;5(252):ra86. doi: 10.1126/scisignal.2003223. Sci Signal. 2012. PMID: 23193159

7

Regulation of protein conformation by Pin1 offers novel disease mechanisms and therapeutic approaches in Alzheimer's disease.

Driver JA, Zhou XZ, Lu KP. Driver JA, et al. Discov Med. 2014 Feb;17(92):93-9. Discov Med. 2014. PMID: 24534472 Free PMC article. Review.

8

Chemical or genetic Pin1 inhibition exerts potent anticancer activity against hepatocellular carcinoma by blocking multiple cancer-driving pathways.

Liao XH, Zhang AL, Zheng M, Li MQ, Chen CP, Xu H, Chu QS, Yang D, Lu W, Tsai TF, Liu H, Zhou XZ, Lu KP. Liao XH, et al. Sci Rep. 2017 Mar 6;7:43639. doi: 10.1038/srep43639. Sci Rep. 2017. PMID: 28262728 Free PMC article.

9

Theileria parasites secrete a prolyl isomerase to maintain host leukocyte transformation.

Marsolier J, Perichon M, DeBarry JD, Villoutreix BO, Chluba J, Lopez T, Garrido C, Zhou XZ, Lu KP, Fritsch L, Ait-Si-Ali S, Mhadhbi M, Medjkane S, Weitzman JB. Marsolier J, et al. Nature. 2015 Apr 16;520(7547):378-82. doi: 10.1038/nature14044. Epub 2015 Jan 26. Nature. 2015. PMID: 25624101 Free PMC article.

10

Arsenic targets Pin1 and cooperates with retinoic acid to inhibit cancer-driving pathways and tumor-initiating cells.

Kozono S, Lin YM, Seo HS, Pinch B, Lian X, Qiu C, Herbert MK, Chen CH, Tan L, Gao ZJ, Massefski W, Doctor ZM, Jackson BP, Chen Y, Dhe-Paganon S, Lu KP, Zhou XZ. Kozono S, et al. Nat Commun. 2018 Aug 9;9(1):3069. doi: 10.1038/s41467-018-05402-2. Nat Commun. 2018. PMID: 30093655 Free PMC article.

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