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Page 1
Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis.
Zhang T, Yin C, Boyd DF, Quarato G, Ingram JP, Shubina M, Ragan KB, Ishizuka T, Crawford JC, Tummers B, Rodriguez DA, Xue J, Peri S, Kaiser WJ, López CB, Xu Y, Upton JW, Thomas PG, Green DR, Balachandran S. Zhang T, et al. Cell. 2020 Mar 19;180(6):1115-1129.e13. doi: 10.1016/j.cell.2020.02.050. Cell. 2020. PMID: 32200799 Free PMC article.
ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis.
Zhang T, Yin C, Fedorov A, Qiao L, Bao H, Beknazarov N, Wang S, Gautam A, Williams RM, Crawford JC, Peri S, Studitsky V, Beg AA, Thomas PG, Walkley C, Xu Y, Poptsova M, Herbert A, Balachandran S. Zhang T, et al. Nature. 2022 Jun;606(7914):594-602. doi: 10.1038/s41586-022-04753-7. Epub 2022 May 25. Nature. 2022. PMID: 35614224 Free PMC article.
Targeting RIPK1 for the treatment of human diseases.
Degterev A, Ofengeim D, Yuan J. Degterev A, et al. Proc Natl Acad Sci U S A. 2019 May 14;116(20):9714-9722. doi: 10.1073/pnas.1901179116. Epub 2019 May 2. Proc Natl Acad Sci U S A. 2019. PMID: 31048504 Free PMC article. Review.
RIPK3-driven cell death during virus infections.
Upton JW, Shubina M, Balachandran S. Upton JW, et al. Immunol Rev. 2017 May;277(1):90-101. doi: 10.1111/imr.12539. Immunol Rev. 2017. PMID: 28462524 Free PMC article. Review.
DAI Senses Influenza A Virus Genomic RNA and Activates RIPK3-Dependent Cell Death.
Thapa RJ, Ingram JP, Ragan KB, Nogusa S, Boyd DF, Benitez AA, Sridharan H, Kosoff R, Shubina M, Landsteiner VJ, Andrake M, Vogel P, Sigal LJ, tenOever BR, Thomas PG, Upton JW, Balachandran S. Thapa RJ, et al. Cell Host Microbe. 2016 Nov 9;20(5):674-681. doi: 10.1016/j.chom.2016.09.014. Epub 2016 Oct 13. Cell Host Microbe. 2016. PMID: 27746097 Free PMC article.
Cell-specific activation of RIPK1 and MLKL after intracerebral hemorrhage in mice.
Lule S, Wu L, Sarro-Schwartz A, Edmiston WJ 3rd, Izzy S, Songtachalert T, Ahn SH, Fernandes ND, Jin G, Chung JY, Balachandran S, Lo EH, Kaplan D, Degterev A, Whalen MJ. Lule S, et al. J Cereb Blood Flow Metab. 2021 Jul;41(7):1623-1633. doi: 10.1177/0271678X20973609. Epub 2020 Nov 19. J Cereb Blood Flow Metab. 2021. PMID: 33210566 Free PMC article.
23 results