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Page 1
Molecular basis of ETV6-mediated predisposition to childhood acute lymphoblastic leukemia.
Nishii R, Baskin-Doerfler R, Yang W, Oak N, Zhao X, Yang W, Hoshitsuki K, Bloom M, Verbist K, Burns M, Li Z, Lin TN, Qian M, Moriyama T, Gastier-Foster JM, Rabin KR, Raetz E, Mullighan C, Pui CH, Yeoh AE, Zhang J, Metzger ML, Klco JM, Hunger SP, Newman S, Wu G, Loh ML, Nichols KE, Yang JJ. Nishii R, et al. Blood. 2021 Jan 21;137(3):364-373. doi: 10.1182/blood.2020006164. Blood. 2021. PMID: 32693409 Free PMC article.
Clinical significance of novel subtypes of acute lymphoblastic leukemia in the context of minimal residual disease-directed therapy.
Jeha S, Choi J, Roberts KG, Pei D, Coustan-Smith E, Inaba H, Rubnitz JE, Ribeiro RC, Gruber TA, Raimondi SC, Karol SE, Qu C, Brady SW, Gu Z, Yang JJ, Cheng C, Downing JR, Evans WE, Relling MV, Campana D, Mullighan CG, Pui CH. Jeha S, et al. Blood Cancer Discov. 2021 Jul;2(4):326-337. doi: 10.1158/2643-3230.BCD-20-0229. Blood Cancer Discov. 2021. PMID: 34250504 Free PMC article.
Germline RUNX1 variation and predisposition to childhood acute lymphoblastic leukemia.
Li Y, Yang W, Devidas M, Winter SS, Kesserwan C, Yang W, Dunsmore KP, Smith C, Qian M, Zhao X, Zhang R, Gastier-Foster JM, Raetz EA, Carroll WL, Li C, Liu PP, Rabin KR, Sanda T, Mullighan CG, Nichols KE, Evans WE, Pui CH, Hunger SP, Teachey DT, Relling MV, Loh ML, Yang JJ. Li Y, et al. J Clin Invest. 2021 Jun 24;131(17):e147898. doi: 10.1172/JCI147898. Online ahead of print. J Clin Invest. 2021. PMID: 34166225 Free PMC article.
ETV6 represses inflammatory response genes and regulates HSPC function during stress hematopoiesis in mice.
Bloom M, Oak N, Baskin-Doerfler R, Feng R, Iacobucci I, Baviskar P, Zhao X, Stroh AN, Li C, Ozark P, Tillman HS, Li Y, Verbist KC, Albeituni S, Scott DC, King MT, McKinney-Freeman SL, Weiss MJ, Yang JJ, Nichols KE. Bloom M, et al. Blood Adv. 2023 Sep 26;7(18):5608-5623. doi: 10.1182/bloodadvances.2022009313. Blood Adv. 2023. PMID: 37522715 Free PMC article.
Immune stress suppresses innate immune signaling in preleukemic precursor B-cells to provoke leukemia in predisposed mice.
Isidro-Hernández M, Casado-García A, Oak N, Alemán-Arteaga S, Ruiz-Corzo B, Martínez-Cano J, Mayado A, Sánchez EG, Blanco O, Gaspar ML, Orfao A, Alonso-López D, De Las Rivas J, Riesco S, Prieto-Matos P, González-Murillo Á, Criado FJG, Cenador MBG, Ramírez-Orellana M, de Andrés B, Vicente-Dueñas C, Cobaleda C, Nichols KE, Sánchez-García I. Isidro-Hernández M, et al. Nat Commun. 2023 Aug 24;14(1):5159. doi: 10.1038/s41467-023-40961-z. Nat Commun. 2023. PMID: 37620322 Free PMC article.
Update on Recommendations for Surveillance for Children with Predisposition to Hematopoietic Malignancy.
Maese LD, Wlodarski MW, Kim SY, Bertuch AA, Bougeard G, Chang VY, Godley LA, Khincha PP, Kuiper RP, Lesmana H, McGee RB, McReynolds LJ, Meade J, Plon SE, Savage SA, Scollon SR, Scott HS, Walsh MF, Nichols KE, Porter CC. Maese LD, et al. Clin Cancer Res. 2024 Oct 1;30(19):4286-4295. doi: 10.1158/1078-0432.CCR-24-0685. Clin Cancer Res. 2024. PMID: 39078402 Review.
Association of Genetic Ancestry With the Molecular Subtypes and Prognosis of Childhood Acute Lymphoblastic Leukemia.
Lee SHR, Antillon-Klussmann F, Pei D, Yang W, Roberts KG, Li Z, Devidas M, Yang W, Najera C, Lin HP, Tan AM, Ariffin H, Cheng C, Evans WE, Hunger SP, Jeha S, Mullighan CG, Loh ML, Yeoh AEJ, Pui CH, Yang JJ. Lee SHR, et al. JAMA Oncol. 2022 Mar 1;8(3):354-363. doi: 10.1001/jamaoncol.2021.6826. JAMA Oncol. 2022. PMID: 35084434 Free PMC article.
15 results