R01 CA250529/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2021	2
2022	3
2023	4
2024	0

1

MEK Inhibition Sensitizes Pancreatic Cancer to STING Agonism by Tumor Cell-intrinsic Amplification of Type I IFN Signaling.

Ghukasyan R, Liang K, Chau K, Li L, Chan C, Abt ER, Le T, Park JY, Wu N, Premji A, Damoiseaux R, Luu T, Labora A, Rashid K, Link JM, Radu CG, Donahue TR. Ghukasyan R, et al. Clin Cancer Res. 2023 Aug 15;29(16):3130-3141. doi: 10.1158/1078-0432.CCR-22-3322. Clin Cancer Res. 2023. PMID: 37195712 Free PMC article.

2

NAD⁺ depletion by type I interferon signaling sensitizes pancreatic cancer cells to NAMPT inhibition.

Moore AM, Zhou L, Cui J, Li L, Wu N, Yu A, Poddar S, Liang K, Abt ER, Kim S, Ghukasyan R, Khachatourian N, Pagano K, Elliott I, Dann AM, Riahi R, Le T, Dawson DW, Radu CG, Donahue TR. Moore AM, et al. Proc Natl Acad Sci U S A. 2021 Feb 23;118(8):e2012469118. doi: 10.1073/pnas.2012469118. Proc Natl Acad Sci U S A. 2021. PMID: 33597293 Free PMC article.

3

STING-driven interferon signaling triggers metabolic alterations in pancreas cancer cells visualized by [¹⁸F]FLT PET imaging.

Liang K, Abt ER, Le TM, Cho A, Dann AM, Cui J, Li L, Rashid K, Creech AL, Wei L, Ghukasyan R, Rosser EW, Wu N, Carlucci G, Czernin J, Donahue TR, Radu CG. Liang K, et al. Proc Natl Acad Sci U S A. 2021 Sep 7;118(36):e2105390118. doi: 10.1073/pnas.2105390118. Proc Natl Acad Sci U S A. 2021. PMID: 34480004 Free PMC article.

4

Purine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity.

Abt ER, Rashid K, Le TM, Li S, Lee HR, Lok V, Li L, Creech AL, Labora AN, Mandl HK, Lam AK, Cho A, Rezek V, Wu N, Abril-Rodriguez G, Rosser EW, Mittelman SD, Hugo W, Mehrling T, Bantia S, Ribas A, Donahue TR, Crooks GM, Wu TT, Radu CG. Abt ER, et al. J Clin Invest. 2022 Aug 15;132(16):e160852. doi: 10.1172/JCI160852. J Clin Invest. 2022. PMID: 35653193 Free PMC article.

5

¹⁸F-FDG PET Visualizes Systemic STING Agonist-Induced Lymphocyte Activation in Preclinical Models.

Le TM, Lee HR, Abt ER, Rashid K, Creech AL, Liang K, Cui J, Cho A, Wei L, Labora A, Chan C, Sanchez E, Kriti K, Karin D, Li L, Wu N, Mona C, Carlucci G, Hugo W, Wu TT, Donahue TR, Czernin J, Radu CG. Le TM, et al. J Nucl Med. 2023 Jan;64(1):117-123. doi: 10.2967/jnumed.122.264121. Epub 2022 Jun 23. J Nucl Med. 2023. PMID: 35738905 Free PMC article.

6

Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells.

Abt ER, Le TM, Dann AM, Capri JR, Poddar S, Lok V, Li L, Liang K, Creech AL, Rashid K, Kim W, Wu N, Cui J, Cho A, Lee HR, Rosser EW, Link JM, Czernin J, Wu TT, Damoiseaux R, Dawson DW, Donahue TR, Radu CG. Abt ER, et al. Cell Rep. 2022 Jan 11;38(2):110236. doi: 10.1016/j.celrep.2021.110236. Cell Rep. 2022. PMID: 35021095 Free PMC article.

7

Generation of liver metastases in a mouse model using ultrasound-guided intravenous injection.

Labora A, Lee H, Chan C, Tabornal E, Le T, Rashid K, Abt E, Yamao T, Mandl H, Creech A, Premji A, Li L, Link J, Wu N, Radu C, Donahue T. Labora A, et al. STAR Protoc. 2023 Mar 15;4(2):102163. doi: 10.1016/j.xpro.2023.102163. Online ahead of print. STAR Protoc. 2023. PMID: 36930646 Free PMC article.

8

Establishing a mouse model of lung metastases using ultrasound-guided right heart ventricle injection.

Labora A, Creech A, Lee H, Tabornal E, Radu C, Donahue T. Labora A, et al. STAR Protoc. 2023 Dec 15;4(4):102698. doi: 10.1016/j.xpro.2023.102698. Epub 2023 Nov 4. STAR Protoc. 2023. PMID: 37925631 Free PMC article.

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