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EMT-activated secretory and endocytic vesicular trafficking programs underlie a vulnerability to PI4K2A antagonism in lung cancer.
J Clin Invest. 2023 Apr 3;133(7):e165863. doi: 10.1172/JCI165863.
J Clin Invest. 2023.
PMID: 36757799
Free PMC article.
Chromosomal 3q amplicon encodes essential regulators of secretory vesicles that drive secretory addiction in cancer.
Tan X, Wang S, Xiao GY, Wu C, Liu X, Zhou B, Yu J, Duose DY, Xi Y, Wang J, Gupta K, Pataer A, Roth JA, Kim MP, Chen F, Creighton CJ, Russell WK, Kurie JM.
Tan X, et al.
J Clin Invest. 2024 Apr 25;134(12):e176355. doi: 10.1172/JCI176355. Online ahead of print.
J Clin Invest. 2024.
PMID: 38662435
Free PMC article.
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A protumorigenic secretory pathway activated by p53 deficiency in lung adenocarcinoma.
Tan X, Shi L, Banerjee P, Liu X, Guo HF, Yu J, Bota-Rabassedas N, Rodriguez BL, Gibbons DL, Russell WK, Creighton CJ, Kurie JM.
Tan X, et al.
J Clin Invest. 2021 Jan 4;131(1):e137186. doi: 10.1172/JCI137186.
J Clin Invest. 2021.
PMID: 32931483
Free PMC article.
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