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TIP-1 has PDZ scaffold antagonist activity.
Alewine C, Olsen O, Wade JB, Welling PA. Alewine C, et al. Mol Biol Cell. 2006 Oct;17(10):4200-11. doi: 10.1091/mbc.e06-02-0129. Epub 2006 Jul 19. Mol Biol Cell. 2006. PMID: 16855024 Free PMC article.
From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene.
Wang Y, O'Connell JR, McArdle PF, Wade JB, Dorff SE, Shah SJ, Shi X, Pan L, Rampersaud E, Shen H, Kim JD, Subramanya AR, Steinle NI, Parsa A, Ober CC, Welling PA, Chakravarti A, Weder AB, Cooper RS, Mitchell BD, Shuldiner AR, Chang YP. Wang Y, et al. Proc Natl Acad Sci U S A. 2009 Jan 6;106(1):226-31. doi: 10.1073/pnas.0808358106. Epub 2008 Dec 29. Proc Natl Acad Sci U S A. 2009. PMID: 19114657 Free PMC article.