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Increased renal renin content in mice lacking the Na+/H+ exchanger NHE2.
Hanner F, Chambrey R, Bourgeois S, Meer E, Mucsi I, Rosivall L, Shull GE, Lorenz JN, Eladari D, Peti-Peterdi J. Hanner F, et al. Am J Physiol Renal Physiol. 2008 Apr;294(4):F937-44. doi: 10.1152/ajprenal.00591.2007. Epub 2008 Feb 20. Am J Physiol Renal Physiol. 2008. PMID: 18287398 Free PMC article.
The collecting duct is the major source of prorenin in diabetes.
Kang JJ, Toma I, Sipos A, Meer EJ, Vargas SL, Peti-Peterdi J. Kang JJ, et al. Hypertension. 2008 Jun;51(6):1597-604. doi: 10.1161/HYPERTENSIONAHA.107.107268. Epub 2008 Apr 14. Hypertension. 2008. PMID: 18413493 Free PMC article.