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P2Y2 purinergic receptor gene deletion protects mice from bacterial endotoxin and sepsis-associated liver injury and mortality.
Arunachalam AR, Samuel SS, Mani A, Maynard JP, Stayer KM, Dybbro E, Narayanan S, Biswas A, Pathan S, Soni K, Kamal AHM, Ambati CSR, Putluri N, Desai MS, Thevananther S. Arunachalam AR, et al. Am J Physiol Gastrointest Liver Physiol. 2023 Nov 1;325(5):G471-G491. doi: 10.1152/ajpgi.00090.2023. Epub 2023 Sep 12. Am J Physiol Gastrointest Liver Physiol. 2023. PMID: 37697947 Free PMC article.
SRC-2 orchestrates polygenic inputs for fine-tuning glucose homeostasis.
Fleet T, Zhang B, Lin F, Zhu B, Dasgupta S, Stashi E, Tackett B, Thevananther S, Rajapakshe KI, Gonzales N, Dean A, Mao J, Timchenko N, Malovannaya A, Qin J, Coarfa C, DeMayo F, Dacso CC, Foulds CE, O'Malley BW, York B. Fleet T, et al. Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):E6068-77. doi: 10.1073/pnas.1519073112. Epub 2015 Oct 20. Proc Natl Acad Sci U S A. 2015. PMID: 26487680 Free PMC article.
ATP release after partial hepatectomy regulates liver regeneration in the rat.
Gonzales E, Julien B, Serrière-Lanneau V, Nicou A, Doignon I, Lagoudakis L, Garcin I, Azoulay D, Duclos-Vallée JC, Castaing D, Samuel D, Hernandez-Garcia A, Awad SS, Combettes L, Thevananther S, Tordjmann T. Gonzales E, et al. J Hepatol. 2010 Jan;52(1):54-62. doi: 10.1016/j.jhep.2009.10.005. Epub 2009 Oct 24. J Hepatol. 2010. PMID: 19914731 Free PMC article.
P2Y2 purinergic receptor activation is essential for efficient hepatocyte proliferation in response to partial hepatectomy.
Tackett BC, Sun H, Mei Y, Maynard JP, Cheruvu S, Mani A, Hernandez-Garcia A, Vigneswaran N, Karpen SJ, Thevananther S. Tackett BC, et al. Am J Physiol Gastrointest Liver Physiol. 2014 Dec 1;307(11):G1073-87. doi: 10.1152/ajpgi.00092.2014. Epub 2014 Oct 9. Am J Physiol Gastrointest Liver Physiol. 2014. PMID: 25301185 Free PMC article.