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32 results

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Page 1
QSER1 protects DNA methylation valleys from de novo methylation.
Dixon G, Pan H, Yang D, Rosen BP, Jashari T, Verma N, Pulecio J, Caspi I, Lee K, Stransky S, Glezer A, Liu C, Rivas M, Kumar R, Lan Y, Torregroza I, He C, Sidoli S, Evans T, Elemento O, Huangfu D. Dixon G, et al. Science. 2021 Apr 9;372(6538):eabd0875. doi: 10.1126/science.abd0875. Science. 2021. PMID: 33833093 Free PMC article.
CRISPR/Cas9-Based Engineering of the Epigenome.
Pulecio J, Verma N, Mejía-Ramírez E, Huangfu D, Raya A. Pulecio J, et al. Cell Stem Cell. 2017 Oct 5;21(4):431-447. doi: 10.1016/j.stem.2017.09.006. Cell Stem Cell. 2017. PMID: 28985525 Free PMC article. Review.
CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restriction.
Yang D, Cho H, Tayyebi Z, Shukla A, Luo R, Dixon G, Ursu V, Stransky S, Tremmel DM, Sackett SD, Koche R, Kaplan SJ, Li QV, Park J, Zhu Z, Rosen BP, Pulecio J, Shi ZD, Bram Y, Schwartz RE, Odorico JS, Sidoli S, Wright CV, Leslie CS, Huangfu D. Yang D, et al. Nat Cell Biol. 2022 Jul;24(7):1064-1076. doi: 10.1038/s41556-022-00946-4. Epub 2022 Jul 4. Nat Cell Biol. 2022. PMID: 35787684 Free PMC article.
Enhancer Predictions and Genome-Wide Regulatory Circuits.
Beer MA, Shigaki D, Huangfu D. Beer MA, et al. Annu Rev Genomics Hum Genet. 2020 Aug 31;21:37-54. doi: 10.1146/annurev-genom-121719-010946. Epub 2020 May 22. Annu Rev Genomics Hum Genet. 2020. PMID: 32443951 Free PMC article. Review.
Dynamic network-guided CRISPRi screen identifies CTCF-loop-constrained nonlinear enhancer gene regulatory activity during cell state transitions.
Luo R, Yan J, Oh JW, Xi W, Shigaki D, Wong W, Cho HS, Murphy D, Cutler R, Rosen BP, Pulecio J, Yang D, Glenn RA, Chen T, Li QV, Vierbuchen T, Sidoli S, Apostolou E, Huangfu D, Beer MA. Luo R, et al. Nat Genet. 2023 Aug;55(8):1336-1346. doi: 10.1038/s41588-023-01450-7. Epub 2023 Jul 24. Nat Genet. 2023. PMID: 37488417 Free PMC article.
Genetic Engineering of Immune Evasive Stem Cell-Derived Islets.
Sackett SD, Kaplan SJ, Mitchell SA, Brown ME, Burrack AL, Grey S, Huangfu D, Odorico J. Sackett SD, et al. Transpl Int. 2022 Dec 5;35:10817. doi: 10.3389/ti.2022.10817. eCollection 2022. Transpl Int. 2022. PMID: 36545154 Free PMC article. Review.
32 results