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Immune regulation by fungal strain diversity in inflammatory bowel disease.
Li XV, Leonardi I, Putzel GG, Semon A, Fiers WD, Kusakabe T, Lin WY, Gao IH, Doron I, Gutierrez-Guerrero A, DeCelie MB, Carriche GM, Mesko M, Yang C, Naglik JR, Hube B, Scherl EJ, Iliev ID. Li XV, et al. Nature. 2022 Mar;603(7902):672-678. doi: 10.1038/s41586-022-04502-w. Epub 2022 Mar 16. Nature. 2022. PMID: 35296857 Free PMC article.
Macrophages Maintain Epithelium Integrity by Limiting Fungal Product Absorption.
Chikina AS, Nadalin F, Maurin M, San-Roman M, Thomas-Bonafos T, Li XV, Lameiras S, Baulande S, Henri S, Malissen B, Lacerda Mariano L, Barbazan J, Blander JM, Iliev ID, Matic Vignjevic D, Lennon-Duménil AM. Chikina AS, et al. Cell. 2020 Oct 15;183(2):411-428.e16. doi: 10.1016/j.cell.2020.08.048. Epub 2020 Sep 23. Cell. 2020. PMID: 32970988 Free PMC article.
Selection of cross-reactive T cells by commensal and food-derived yeasts drives cytotoxic TH1 cell responses in Crohn's disease.
Martini GR, Tikhonova E, Rosati E, DeCelie MB, Sievers LK, Tran F, Lessing M, Bergfeld A, Hinz S, Nikolaus S, Kümpers J, Matysiak A, Hofmann P, Saggau C, Schneiders S, Kamps AK, Jacobs G, Lieb W, Maul J, Siegmund B, Seegers B, Hinrichsen H, Oberg HH, Wesch D, Bereswill S, Heimesaat MM, Rupp J, Kniemeyer O, Brakhage AA, Brunke S, Hube B, Aden K, Franke A, Iliev ID, Scheffold A, Schreiber S, Bacher P. Martini GR, et al. Nat Med. 2023 Oct;29(10):2602-2614. doi: 10.1038/s41591-023-02556-5. Epub 2023 Sep 25. Nat Med. 2023. PMID: 37749331 Free PMC article.
Fungal microbiota sustains lasting immune activation of neutrophils and their progenitors in severe COVID-19.
Kusakabe T, Lin WY, Cheong JG, Singh G, Ravishankar A, Yeung ST, Mesko M, DeCelie MB, Carriche G, Zhao Z, Rand S, Doron I, Putzel GG, Worgall S, Cushing M, Westblade L, Inghirami G, Parkhurst CN, Guo CJ, Schotsaert M, García-Sastre A, Josefowicz SZ, Salvatore M, Iliev ID. Kusakabe T, et al. Nat Immunol. 2023 Nov;24(11):1879-1889. doi: 10.1038/s41590-023-01637-4. Epub 2023 Oct 23. Nat Immunol. 2023. PMID: 37872315 Free PMC article.
Gut epithelium modulates fungal pathogenesis.
Lin WY, Iliev ID. Lin WY, et al. Science. 2023 Aug 4;381(6657):483-484. doi: 10.1126/science.adj1240. Epub 2023 Aug 3. Science. 2023. PMID: 37535732 Free PMC article.
When IL-17 gets on your nerves.
Iliev ID, Lin WY, Gaffen SL. Iliev ID, et al. Cell. 2023 Feb 2;186(3):466-468. doi: 10.1016/j.cell.2022.12.048. Cell. 2023. PMID: 36736299 Free PMC article.
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