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Metabolism and Colorectal Cancer.
Sedlak JC, Yilmaz ÖH, Roper J. Sedlak JC, et al. Annu Rev Pathol. 2023 Jan 24;18:467-492. doi: 10.1146/annurev-pathmechdis-031521-041113. Epub 2022 Nov 2. Annu Rev Pathol. 2023. PMID: 36323004 Free PMC article. Review.
Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis.
Beyaz S, Chung C, Mou H, Bauer-Rowe KE, Xifaras ME, Ergin I, Dohnalova L, Biton M, Shekhar K, Eskiocak O, Papciak K, Ozler K, Almeqdadi M, Yueh B, Fein M, Annamalai D, Valle-Encinas E, Erdemir A, Dogum K, Shah V, Alici-Garipcan A, Meyer HV, Özata DM, Elinav E, Kucukural A, Kumar P, McAleer JP, Fox JG, Thaiss CA, Regev A, Roper J, Orkin SH, Yilmaz ÖH. Beyaz S, et al. Cell Stem Cell. 2021 Nov 4;28(11):1922-1935.e5. doi: 10.1016/j.stem.2021.08.007. Epub 2021 Sep 15. Cell Stem Cell. 2021. PMID: 34529935 Free PMC article.
Post-fast refeeding enhances intestinal stem cell-mediated regeneration and tumourigenesis through mTORC1-dependent polyamine synthesis.
Imada S, Shin H, Khawaled S, Meckelmann SW, Whittaker CA, Corrêa RO, Pradhan D, Calibasi-Kocal G, Melo LMN, Allies G, Wittenhofer P, Schmitz OJ, Roper J, Vinolo MAR, Cheng CW, Tasdogan A, Yilmaz ÖH. Imada S, et al. Res Sq [Preprint]. 2023 Jan 10:rs.3.rs-2320717. doi: 10.21203/rs.3.rs-2320717/v1. Res Sq. 2023. Update in: Nature. 2024 Sep;633(8031):895-904. doi: 10.1038/s41586-024-07840-z PMID: 36711807 Free PMC article. Updated. Preprint.
Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation.
Kummerlowe C, Mwakamui S, Hughes TK, Mulugeta N, Mudenda V, Besa E, Zyambo K, Shay JES, Fleming I, Vukovic M, Doran BA, Aicher TP, Wadsworth MH 2nd, Bramante JT, Uchida AM, Fardoos R, Asowata OE, Herbert N, Yilmaz ÖH, Kløverpris HN, Garber JJ, Ordovas-Montañes J, Gartner ZJ, Wallach T, Shalek AK, Kelly P. Kummerlowe C, et al. Sci Transl Med. 2022 Aug 31;14(660):eabi8633. doi: 10.1126/scitranslmed.abi8633. Epub 2022 Aug 31. Sci Transl Med. 2022. PMID: 36044598 Free PMC article.
Irreversible depletion of intestinal CD4+ T cells is associated with T cell activation during chronic HIV infection.
Asowata OE, Singh A, Ngoepe A, Herbert N, Fardoos R, Reddy K, Zungu Y, Nene F, Mthabela N, Ramjit D, Karim F, Govender K, Ndung'u T, Porterfield JZ, Adamson JH, Madela FG, Manzini VT, Anderson F, Leslie A, Kløverpris HN. Asowata OE, et al. JCI Insight. 2021 Nov 22;6(22):e146162. doi: 10.1172/jci.insight.146162. JCI Insight. 2021. PMID: 34618690 Free PMC article.