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Cataract-linked serine mutations in the gap junction protein connexin50 expose a sorting signal that promotes its lysosomal degradation.
J Biol Chem. 2022 Mar;298(3):101673. doi: 10.1016/j.jbc.2022.101673. Epub 2022 Feb 2.
J Biol Chem. 2022.
PMID: 35120923
Free PMC article.
Calcium-Activated Chloride Channels in Newly Differentiating Mouse Lens Fiber Cells and Their Role in Volume Regulation.
Tong JJ, Acharya P, Ebihara L.
Tong JJ, et al.
Invest Ophthalmol Vis Sci. 2019 Apr 1;60(5):1621-1629. doi: 10.1167/iovs.19-26626.
Invest Ophthalmol Vis Sci. 2019.
PMID: 30995319
Free PMC article.
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Molecular mechanisms underlying enhanced hemichannel function of a cataract-associated Cx50 mutant.
Tong JJ, Khan U, Haddad BG, Minogue PJ, Beyer EC, Berthoud VM, Reichow SL, Ebihara L.
Tong JJ, et al.
Biophys J. 2021 Dec 21;120(24):5644-5656. doi: 10.1016/j.bpj.2021.11.004. Epub 2021 Nov 9.
Biophys J. 2021.
PMID: 34762867
Free PMC article.
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