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Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins.
Trends Biochem Sci. 2011 Oct;36(10):501-14. doi: 10.1016/j.tibs.2011.07.001. Epub 2011 Aug 17.
Trends Biochem Sci. 2011.
PMID: 21852138
Free PMC article.
Review.
Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function.
Lee TH, Chen CH, Suizu F, Huang P, Schiene-Fischer C, Daum S, Zhang YJ, Goate A, Chen RH, Zhou XZ, Lu KP.
Lee TH, et al.
Mol Cell. 2011 Apr 22;42(2):147-59. doi: 10.1016/j.molcel.2011.03.005. Epub 2011 Apr 14.
Mol Cell. 2011.
PMID: 21497122
Free PMC article.
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A PIN1 polymorphism that prevents its suppression by AP4 associates with delayed onset of Alzheimer's disease.
Ma SL, Tang NL, Tam CW, Lui VW, Lam LC, Chiu HF, Driver JA, Pastorino L, Lu KP.
Ma SL, et al.
Neurobiol Aging. 2012 Apr;33(4):804-13. doi: 10.1016/j.neurobiolaging.2010.05.018. Epub 2010 Jun 30.
Neurobiol Aging. 2012.
PMID: 20580132
Free PMC article.
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