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Page 1
Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation.
Roberts MA, Deol KK, Mathiowetz AJ, Lange M, Leto DE, Stevenson J, Hashemi SH, Morgens DW, Easter E, Heydari K, Nalls MA, Bassik MC, Kampmann M, Kopito RR, Faghri F, Olzmann JA. Roberts MA, et al. Dev Cell. 2023 Sep 25;58(18):1782-1800.e10. doi: 10.1016/j.devcel.2023.07.001. Epub 2023 Jul 25. Dev Cell. 2023. PMID: 37494933 Free PMC article.
UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER.
DaRosa PA, Penchev I, Gumbin SC, Scavone F, Wąchalska M, Paulo JA, Ordureau A, Peter JJ, Kulathu Y, Harper JW, Becker T, Beckmann R, Kopito RR. DaRosa PA, et al. Nature. 2024 Mar;627(8003):445-452. doi: 10.1038/s41586-024-07073-0. Epub 2024 Feb 21. Nature. 2024. PMID: 38383785 Free PMC article.
Ribosomal protein RPL26 is the principal target of UFMylation.
Walczak CP, Leto DE, Zhang L, Riepe C, Muller RY, DaRosa PA, Ingolia NT, Elias JE, Kopito RR. Walczak CP, et al. Proc Natl Acad Sci U S A. 2019 Jan 22;116(4):1299-1308. doi: 10.1073/pnas.1816202116. Epub 2019 Jan 9. Proc Natl Acad Sci U S A. 2019. PMID: 30626644 Free PMC article.
The herpesvirus UL49.5 protein hijacks a cellular C-degron pathway to drive TAP transporter degradation.
Wąhalska M, Riepe C, Ślusarz MJ, Graul M, Borowski LS, Qiao W, Foltynska M, Carette JE, Bieńkowska-Szewczyk K, Szczesny RJ, Kopito RR, Lipińska AD. Wąhalska M, et al. bioRxiv [Preprint]. 2023 Sep 27:2023.09.27.559663. doi: 10.1101/2023.09.27.559663. bioRxiv. 2023. Update in: Proc Natl Acad Sci U S A. 2024 Mar 12;121(11):e2309841121. doi: 10.1073/pnas.2309841121. PMID: 37808699 Free PMC article. Updated. Preprint.
26 results