R01 GM082834-01/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

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Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis.

Castoreno AB, Smurnyy Y, Torres AD, Vokes MS, Jones TR, Carpenter AE, Eggert US. Castoreno AB, et al. Nat Chem Biol. 2010 Jun;6(6):457-63. doi: 10.1038/nchembio.363. Epub 2010 May 2. Nat Chem Biol. 2010. PMID: 20436488 Free PMC article.

Binucleine 2, an isoform-specific inhibitor of Drosophila Aurora B kinase, provides insights into the mechanism of cytokinesis.

Smurnyy Y, Toms AV, Hickson GR, Eck MJ, Eggert US. Smurnyy Y, et al. ACS Chem Biol. 2010 Nov 19;5(11):1015-20. doi: 10.1021/cb1001685. ACS Chem Biol. 2010. PMID: 20804174 Free PMC article.

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