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Protein accounting in the cellular economy.
Vázquez-Laslop N, Mankin AS. Vázquez-Laslop N, et al. Cell. 2014 Apr 24;157(3):529-31. doi: 10.1016/j.cell.2014.04.002. Cell. 2014. PMID: 24766801 Free PMC article.
Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Polikanov YS, Osterman IA, Szal T, Tashlitsky VN, Serebryakova MV, Kusochek P, Bulkley D, Malanicheva IA, Efimenko TA, Efremenkova OV, Konevega AL, Shaw KJ, Bogdanov AA, Rodnina MV, Dontsova OA, Mankin AS, Steitz TA, Sergiev PV. Polikanov YS, et al. Mol Cell. 2014 Nov 20;56(4):531-40. doi: 10.1016/j.molcel.2014.09.020. Epub 2014 Oct 9. Mol Cell. 2014. PMID: 25306919 Free PMC article.
Macrolide antibiotics allosterically predispose the ribosome for translation arrest.
Sothiselvam S, Liu B, Han W, Ramu H, Klepacki D, Atkinson GC, Brauer A, Remm M, Tenson T, Schulten K, Vázquez-Laslop N, Mankin AS. Sothiselvam S, et al. Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9804-9. doi: 10.1073/pnas.1403586111. Epub 2014 Jun 24. Proc Natl Acad Sci U S A. 2014. PMID: 24961372 Free PMC article.