R01 GM131168/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2019	3
2020	3
2021	6
2022	8
2023	7
2024	0

1

Site-specific dual encoding and labeling of proteins via genetic code expansion.

Bednar RM, Karplus PA, Mehl RA. Bednar RM, et al. Cell Chem Biol. 2023 Apr 20;30(4):343-361. doi: 10.1016/j.chembiol.2023.03.004. Epub 2023 Mar 27. Cell Chem Biol. 2023. PMID: 36977415 Free PMC article. Review.

2

Genetically Encoded Protein Tyrosine Nitration in Mammalian Cells.

Porter JJ, Jang HS, Van Fossen EM, Nguyen DP, Willi TS, Cooley RB, Mehl RA. Porter JJ, et al. ACS Chem Biol. 2019 Jun 21;14(6):1328-1336. doi: 10.1021/acschembio.9b00371. Epub 2019 Jun 4. ACS Chem Biol. 2019. PMID: 31117397 Free PMC article.

3

Biosynthesis and Genetic Encoding of Non-hydrolyzable Phosphoserine into Recombinant Proteins in Escherichia coli.

Zhu P, Mehl RA, Cooley RB. Zhu P, et al. Bio Protoc. 2023 Nov 5;13(21):e4861. doi: 10.21769/BioProtoc.4861. eCollection 2023 Nov 5. Bio Protoc. 2023. PMID: 37969748 Free PMC article.

4

Truncation-Free Genetic Code Expansion with Tetrazine Amino Acids for Quantitative Protein Ligations.

Eddins AJ, Bednar RM, Jana S, Pung AH, Mbengi L, Meyer K, Perona JJ, Cooley RB, Karplus PA, Mehl RA. Eddins AJ, et al. Bioconjug Chem. 2023 Dec 20;34(12):2243-2254. doi: 10.1021/acs.bioconjchem.3c00380. Epub 2023 Dec 4. Bioconjug Chem. 2023. PMID: 38047550

5

Access to Faster Eukaryotic Cell Labeling with Encoded Tetrazine Amino Acids.

Jang HS, Jana S, Blizzard RJ, Meeuwsen JC, Mehl RA. Jang HS, et al. J Am Chem Soc. 2020 Apr 22;142(16):7245-7249. doi: 10.1021/jacs.9b11520. Epub 2020 Apr 10. J Am Chem Soc. 2020. PMID: 32251579 Free PMC article.

6

Faster Surface Ligation Reactions Improve Immobilized Enzyme Structure and Activity.

Chaparro Sosa AF, Bednar RM, Mehl RA, Schwartz DK, Kaar JL. Chaparro Sosa AF, et al. J Am Chem Soc. 2021 May 12;143(18):7154-7163. doi: 10.1021/jacs.1c02375. Epub 2021 Apr 29. J Am Chem Soc. 2021. PMID: 33914511 Free PMC article.

7

Creating a Selective Nanobody Against 3-Nitrotyrosine Containing Proteins.

Van Fossen EM, Grutzius S, Ruby CE, Mourich DV, Cebra C, Bracha S, Karplus PA, Cooley RB, Mehl RA. Van Fossen EM, et al. Front Chem. 2022 Feb 21;10:835229. doi: 10.3389/fchem.2022.835229. eCollection 2022. Front Chem. 2022. PMID: 35265586 Free PMC article.

8

Genetic Incorporation of Two Mutually Orthogonal Bioorthogonal Amino Acids That Enable Efficient Protein Dual-Labeling in Cells.

Bednar RM, Jana S, Kuppa S, Franklin R, Beckman J, Antony E, Cooley RB, Mehl RA. Bednar RM, et al. ACS Chem Biol. 2021 Nov 19;16(11):2612-2622. doi: 10.1021/acschembio.1c00649. Epub 2021 Sep 30. ACS Chem Biol. 2021. PMID: 34590824 Free PMC article.

9

Selection and validation of orthogonal tRNA/synthetase pairs for the encoding of unnatural amino acids across kingdoms.

Galles GD, Infield DT, Mehl RA, Ahern CA. Galles GD, et al. Methods Enzymol. 2021;654:3-18. doi: 10.1016/bs.mie.2021.03.009. Epub 2021 Apr 9. Methods Enzymol. 2021. PMID: 34120719

10

Rational Design for High Bioorthogonal Fluorogenicity of Tetrazine-Encoded Green Fluorescent Proteins.

Tang L, Bednar RM, Rozanov ND, Hemshorn ML, Mehl RA, Fang C. Tang L, et al. Nat Sci (Weinh). 2022 Oct;2(4):e20220028. doi: 10.1002/ntls.20220028. Epub 2022 Aug 8. Nat Sci (Weinh). 2022. PMID: 36440454 Free PMC article.

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