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Enhancer switching in cell lineage priming is linked to eRNA, Brg1's AT-hook, and SWI/SNF recruitment.
Mol Cell. 2024 May 16;84(10):1855-1869.e5. doi: 10.1016/j.molcel.2024.03.013. Epub 2024 Apr 8.
Mol Cell. 2024.
PMID: 38593804
The SWI/SNF ATP-dependent chromatin remodeling complex in cell lineage priming and early development.
Saha D, Animireddy S, Bartholomew B.
Saha D, et al.
Biochem Soc Trans. 2024 Apr 24;52(2):603-616. doi: 10.1042/BST20230416.
Biochem Soc Trans. 2024.
PMID: 38572912
Free PMC article.
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The AT-hook is an evolutionarily conserved auto-regulatory domain of SWI/SNF required for cell lineage priming.
Saha D, Hailu S, Hada A, Lee J, Luo J, Ranish JA, Lin YC, Feola K, Persinger J, Jain A, Liu B, Lu Y, Sen P, Bartholomew B.
Saha D, et al.
Nat Commun. 2023 Aug 4;14(1):4682. doi: 10.1038/s41467-023-40386-8.
Nat Commun. 2023.
PMID: 37542049
Free PMC article.
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