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Aggressive very low-density lipoprotein (VLDL) and LDL lowering by gene transfer of the VLDL receptor combined with a low-fat diet regimen induces regression and reduces macrophage content in advanced atherosclerotic lesions in LDL receptor-deficient mice.
MacDougall ED, Kramer F, Polinsky P, Barnhart S, Askari B, Johansson F, Varon R, Rosenfeld ME, Oka K, Chan L, Schwartz SM, Bornfeldt KE. MacDougall ED, et al. Am J Pathol. 2006 Jun;168(6):2064-73. doi: 10.2353/ajpath.2006.051009. Am J Pathol. 2006. PMID: 16723719 Free PMC article.