R01 HL089462/HL/NHLBI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2008	1
2009	2
2011	1
2012	1
2013	3
2015	1
2016	1
2017	1
2024	0

1

Regulation of dynamin-2 assembly-disassembly and function through the SH3A domain of intersectin-1s.

Knezevic I, Predescu D, Bardita C, Wang M, Sharma T, Keith B, Neamu R, Malik AB, Predescu S. Knezevic I, et al. J Cell Mol Med. 2011 Nov;15(11):2364-76. doi: 10.1111/j.1582-4934.2010.01226.x. J Cell Mol Med. 2011. PMID: 21129155 Free PMC article.

2

Endocytic deficiency induced by ITSN-1s knockdown alters the Smad2/3-Erk1/2 signaling balance downstream of Alk5.

Bardita C, Predescu DN, Sha F, Patel M, Balaji G, Predescu SA. Bardita C, et al. J Cell Sci. 2015 Apr 15;128(8):1528-41. doi: 10.1242/jcs.163030. Epub 2015 Feb 26. J Cell Sci. 2015. PMID: 25720380 Free PMC article.

3

Intersectin-2L regulates caveola endocytosis secondary to Cdc42-mediated actin polymerization.

Klein IK, Predescu DN, Sharma T, Knezevic I, Malik AB, Predescu S. Klein IK, et al. J Biol Chem. 2009 Sep 18;284(38):25953-61. doi: 10.1074/jbc.M109.035071. Epub 2009 Jul 21. J Biol Chem. 2009. PMID: 19622753 Free PMC article.

4

Rac1-mediated cytoskeleton rearrangements induced by intersectin-1s deficiency promotes lung cancer cell proliferation, migration and metastasis.

Jeganathan N, Predescu D, Zhang J, Sha F, Bardita C, Patel M, Wood S, Borgia JA, Balk RA, Predescu S. Jeganathan N, et al. Mol Cancer. 2016 Sep 14;15(1):59. doi: 10.1186/s12943-016-0543-1. Mol Cancer. 2016. PMID: 27629044 Free PMC article.

5

Tiam1 and Rac1 are required for platelet-activating factor-induced endothelial junctional disassembly and increase in vascular permeability.

Knezevic II, Predescu SA, Neamu RF, Gorovoy MS, Knezevic NM, Easington C, Malik AB, Predescu DN. Knezevic II, et al. J Biol Chem. 2009 Feb 20;284(8):5381-94. doi: 10.1074/jbc.M808958200. Epub 2008 Dec 17. J Biol Chem. 2009. PMID: 19095647 Free PMC article.

6

Modulation of Intersectin-1s Lung Expression Induces Obliterative Remodeling and Severe Plexiform Arteriopathy in the Murine Pulmonary Vascular Bed.

Patel M, Predescu D, Bardita C, Chen J, Jeganathan N, Pritchard M, DiBartolo S, Machado R, Predescu S. Patel M, et al. Am J Pathol. 2017 Mar;187(3):528-542. doi: 10.1016/j.ajpath.2016.11.012. Epub 2017 Jan 6. Am J Pathol. 2017. PMID: 28068512 Free PMC article.

7

In vivo knockdown of intersectin-1s alters endothelial cell phenotype and causes microvascular remodeling in the mouse lungs.

Bardita C, Predescu D, Justice MJ, Petrache I, Predescu S. Bardita C, et al. Apoptosis. 2013 Jan;18(1):57-76. doi: 10.1007/s10495-012-0762-x. Apoptosis. 2013. PMID: 23054079 Free PMC article.

8

A novel p38 mitogen-activated protein kinase/Elk-1 transcription factor-dependent molecular mechanism underlying abnormal endothelial cell proliferation in plexogenic pulmonary arterial hypertension.

Patel M, Predescu D, Tandon R, Bardita C, Pogoriler J, Bhorade S, Wang M, Comhair S, Ryan-Hemnes A, Chen J, Machado R, Husain A, Erzurum S, Predescu S. Patel M, et al. J Biol Chem. 2013 Sep 6;288(36):25701-25716. doi: 10.1074/jbc.M113.502674. Epub 2013 Jul 26. J Biol Chem. 2013. PMID: 23893408 Free PMC article.

9

Long-term silencing of intersectin-1s in mouse lungs by repeated delivery of a specific siRNA via cationic liposomes. Evaluation of knockdown effects by electron microscopy.

Bardita C, Predescu D, Predescu S. Bardita C, et al. J Vis Exp. 2013 Jun 21;(76):50316. doi: 10.3791/50316. J Vis Exp. 2013. PMID: 23851900 Free PMC article.

10

Impaired caveolae function and upregulation of alternative endocytic pathways induced by experimental modulation of intersectin-1s expression in mouse lung endothelium.

Predescu DN, Neamu R, Bardita C, Wang M, Predescu SA. Predescu DN, et al. Biochem Res Int. 2012;2012:672705. doi: 10.1155/2012/672705. Epub 2012 Feb 26. Biochem Res Int. 2012. PMID: 22506115 Free PMC article.

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