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Animal models of arrhythmogenic cardiomyopathy.
McCauley MD, Wehrens XH. McCauley MD, et al. Dis Model Mech. 2009 Nov-Dec;2(11-12):563-70. doi: 10.1242/dmm.002840. Dis Model Mech. 2009. PMID: 19892887 Free PMC article. Review.
Sudden infant death syndrome in mice with an inherited mutation in RyR2.
Mathur N, Sood S, Wang S, van Oort RJ, Sarma S, Li N, Skapura DG, Bayle JH, Valderrábano M, Wehrens XH. Mathur N, et al. Circ Arrhythm Electrophysiol. 2009 Dec;2(6):677-85. doi: 10.1161/CIRCEP.109.894683. Circ Arrhythm Electrophysiol. 2009. PMID: 20009080 Free PMC article.
Calmodulin kinase II is required for fight or flight sinoatrial node physiology.
Wu Y, Gao Z, Chen B, Koval OM, Singh MV, Guan X, Hund TJ, Kutschke W, Sarma S, Grumbach IM, Wehrens XH, Mohler PJ, Song LS, Anderson ME. Wu Y, et al. Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5972-7. doi: 10.1073/pnas.0806422106. Epub 2009 Mar 10. Proc Natl Acad Sci U S A. 2009. PMID: 19276108 Free PMC article.
Ryanodine receptor phosphorylation by calcium/calmodulin-dependent protein kinase II promotes life-threatening ventricular arrhythmias in mice with heart failure.
van Oort RJ, McCauley MD, Dixit SS, Pereira L, Yang Y, Respress JL, Wang Q, De Almeida AC, Skapura DG, Anderson ME, Bers DM, Wehrens XH. van Oort RJ, et al. Circulation. 2010 Dec 21;122(25):2669-79. doi: 10.1161/CIRCULATIONAHA.110.982298. Epub 2010 Nov 15. Circulation. 2010. PMID: 21098440 Free PMC article.