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Page 1
Update in asthma 2013.
Cohn L, Woodruff PG. Cohn L, et al. Am J Respir Crit Care Med. 2014 Jun 15;189(12):1487-93. doi: 10.1164/rccm.201403-0498UP. Am J Respir Crit Care Med. 2014. PMID: 24930529 Free PMC article. Review. No abstract available.
Muc5b is required for airway defence.
Roy MG, Livraghi-Butrico A, Fletcher AA, McElwee MM, Evans SE, Boerner RM, Alexander SN, Bellinghausen LK, Song AS, Petrova YM, Tuvim MJ, Adachi R, Romo I, Bordt AS, Bowden MG, Sisson JH, Woodruff PG, Thornton DJ, Rousseau K, De la Garza MM, Moghaddam SJ, Karmouty-Quintana H, Blackburn MR, Drouin SM, Davis CW, Terrell KA, Grubb BR, O'Neal WK, Flores SC, Cota-Gomez A, Lozupone CA, Donnelly JM, Watson AM, Hennessy CE, Keith RC, Yang IV, Barthel L, Henson PM, Janssen WJ, Schwartz DA, Boucher RC, Dickey BF, Evans CM. Roy MG, et al. Nature. 2014 Jan 16;505(7483):412-6. doi: 10.1038/nature12807. Epub 2013 Dec 8. Nature. 2014. PMID: 24317696 Free PMC article.
Airway epithelial miRNA expression is altered in asthma.
Solberg OD, Ostrin EJ, Love MI, Peng JC, Bhakta NR, Hou L, Nguyen C, Solon M, Nguyen C, Barczak AJ, Zlock LT, Blagev DP, Finkbeiner WE, Ansel KM, Arron JR, Erle DJ, Woodruff PG. Solberg OD, et al. Am J Respir Crit Care Med. 2012 Nov 15;186(10):965-74. doi: 10.1164/rccm.201201-0027OC. Epub 2012 Sep 6. Am J Respir Crit Care Med. 2012. PMID: 22955319 Free PMC article. Clinical Trial.
A qPCR-based metric of Th2 airway inflammation in asthma.
Bhakta NR, Solberg OD, Nguyen CP, Nguyen CN, Arron JR, Fahy JV, Woodruff PG. Bhakta NR, et al. Clin Transl Allergy. 2013 Jul 17;3(1):24. doi: 10.1186/2045-7022-3-24. Clin Transl Allergy. 2013. PMID: 23866775 Free PMC article.
Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients.
Levänen B, Bhakta NR, Torregrosa Paredes P, Barbeau R, Hiltbrunner S, Pollack JL, Sköld CM, Svartengren M, Grunewald J, Gabrielsson S, Eklund A, Larsson BM, Woodruff PG, Erle DJ, Wheelock ÅM. Levänen B, et al. J Allergy Clin Immunol. 2013 Mar;131(3):894-903. doi: 10.1016/j.jaci.2012.11.039. Epub 2013 Jan 16. J Allergy Clin Immunol. 2013. PMID: 23333113 Free PMC article.
A large subgroup of mild-to-moderate asthma is persistently noneosinophilic.
McGrath KW, Icitovic N, Boushey HA, Lazarus SC, Sutherland ER, Chinchilli VM, Fahy JV; Asthma Clinical Research Network of the National Heart, Lung, and Blood Institute. McGrath KW, et al. Am J Respir Crit Care Med. 2012 Mar 15;185(6):612-9. doi: 10.1164/rccm.201109-1640OC. Epub 2012 Jan 20. Am J Respir Crit Care Med. 2012. PMID: 22268133 Free PMC article. Clinical Trial.
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