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Page 1
Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.
Lewis HD, Liddle J, Coote JE, Atkinson SJ, Barker MD, Bax BD, Bicker KL, Bingham RP, Campbell M, Chen YH, Chung CW, Craggs PD, Davis RP, Eberhard D, Joberty G, Lind KE, Locke K, Maller C, Martinod K, Patten C, Polyakova O, Rise CE, Rüdiger M, Sheppard RJ, Slade DJ, Thomas P, Thorpe J, Yao G, Drewes G, Wagner DD, Thompson PR, Prinjha RK, Wilson DM. Lewis HD, et al. Nat Chem Biol. 2015 Mar;11(3):189-91. doi: 10.1038/nchembio.1735. Epub 2015 Jan 26. Nat Chem Biol. 2015. PMID: 25622091 Free PMC article.
Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo.
von Brühl ML, Stark K, Steinhart A, Chandraratne S, Konrad I, Lorenz M, Khandoga A, Tirniceriu A, Coletti R, Köllnberger M, Byrne RA, Laitinen I, Walch A, Brill A, Pfeiler S, Manukyan D, Braun S, Lange P, Riegger J, Ware J, Eckart A, Haidari S, Rudelius M, Schulz C, Echtler K, Brinkmann V, Schwaiger M, Preissner KT, Wagner DD, Mackman N, Engelmann B, Massberg S. von Brühl ML, et al. J Exp Med. 2012 Apr 9;209(4):819-35. doi: 10.1084/jem.20112322. Epub 2012 Mar 26. J Exp Med. 2012. PMID: 22451716 Free PMC article.
Thrombosis: tangled up in NETs.
Martinod K, Wagner DD. Martinod K, et al. Blood. 2014 May 1;123(18):2768-76. doi: 10.1182/blood-2013-10-463646. Epub 2013 Dec 23. Blood. 2014. PMID: 24366358 Free PMC article. Review.
Priming of neutrophils toward NETosis promotes tumor growth.
Demers M, Wong SL, Martinod K, Gallant M, Cabral JE, Wang Y, Wagner DD. Demers M, et al. Oncoimmunology. 2016 Feb 18;5(5):e1134073. doi: 10.1080/2162402X.2015.1134073. eCollection 2016 May. Oncoimmunology. 2016. PMID: 27467952 Free PMC article.
Peptidylarginine deiminase 4 promotes age-related organ fibrosis.
Martinod K, Witsch T, Erpenbeck L, Savchenko A, Hayashi H, Cherpokova D, Gallant M, Mauler M, Cifuni SM, Wagner DD. Martinod K, et al. J Exp Med. 2017 Feb;214(2):439-458. doi: 10.1084/jem.20160530. Epub 2016 Dec 28. J Exp Med. 2017. PMID: 28031479 Free PMC article.
T granules in human platelets function in TLR9 organization and signaling.
Thon JN, Peters CG, Machlus KR, Aslam R, Rowley J, Macleod H, Devine MT, Fuchs TA, Weyrich AS, Semple JW, Flaumenhaft R, Italiano JE Jr. Thon JN, et al. J Cell Biol. 2012 Aug 20;198(4):561-74. doi: 10.1083/jcb.201111136. J Cell Biol. 2012. PMID: 22908309 Free PMC article.
38 results