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34 results

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Page 1
A transcriptional switch governs fibroblast activation in heart disease.
Alexanian M, Przytycki PF, Micheletti R, Padmanabhan A, Ye L, Travers JG, Gonzalez-Teran B, Silva AC, Duan Q, Ranade SS, Felix F, Linares-Saldana R, Li L, Lee CY, Sadagopan N, Pelonero A, Huang Y, Andreoletti G, Jain R, McKinsey TA, Rosenfeld MG, Gifford CA, Pollard KS, Haldar SM, Srivastava D. Alexanian M, et al. Nature. 2021 Jul;595(7867):438-443. doi: 10.1038/s41586-021-03674-1. Epub 2021 Jun 23. Nature. 2021. PMID: 34163071 Free PMC article.
Histone deacetylase 6 inhibition restores leptin sensitivity and reduces obesity.
Çakır I, Hadley CK, Pan PL, Bagchi RA, Ghamari-Langroudi M, Porter DT, Wang Q, Litt MJ, Jana S, Hagen S, Lee P, White A, Lin JD, McKinsey TA, Cone RD. Çakır I, et al. Nat Metab. 2022 Jan;4(1):44-59. doi: 10.1038/s42255-021-00515-3. Epub 2022 Jan 17. Nat Metab. 2022. PMID: 35039672 Free PMC article.
Chromatin remodelling drives immune cell-fibroblast communication in heart failure.
Alexanian M, Padmanabhan A, Nishino T, Travers JG, Ye L, Pelonero A, Lee CY, Sadagopan N, Huang Y, Auclair K, Zhu A, An Y, Ekstrand CA, Martinez C, Teran BG, Flanigan WR, Kim CK, Lumbao-Conradson K, Gardner Z, Li L, Costa MW, Jain R, Charo I, Combes AJ, Haldar SM, Pollard KS, Vagnozzi RJ, McKinsey TA, Przytycki PF, Srivastava D. Alexanian M, et al. Nature. 2024 Nov;635(8038):434-443. doi: 10.1038/s41586-024-08085-6. Epub 2024 Oct 23. Nature. 2024. PMID: 39443808
HDAC Inhibition Reverses Preexisting Diastolic Dysfunction and Blocks Covert Extracellular Matrix Remodeling.
Travers JG, Wennersten SA, Peña B, Bagchi RA, Smith HE, Hirsch RA, Vanderlinden LA, Lin YH, Dobrinskikh E, Demos-Davies KM, Cavasin MA, Mestroni L, Steinkühler C, Lin CY, Houser SR, Woulfe KC, Lam MPY, McKinsey TA. Travers JG, et al. Circulation. 2021 May 11;143(19):1874-1890. doi: 10.1161/CIRCULATIONAHA.120.046462. Epub 2021 Mar 8. Circulation. 2021. PMID: 33682427 Free PMC article.
Cat-apulting Toward a Molecular Understanding of HFpEF.
Robinson EL, McKinsey TA. Robinson EL, et al. JACC Basic Transl Sci. 2021 Aug 23;6(8):673-675. doi: 10.1016/j.jacbts.2021.07.005. eCollection 2021 Aug. JACC Basic Transl Sci. 2021. PMID: 34466753 Free PMC article.
A Phosphatase Anchor Weighs on the Heart.
Woulfe KC, Travers JG, McKinsey TA. Woulfe KC, et al. Circulation. 2020 Sep 8;142(10):963-966. doi: 10.1161/CIRCULATIONAHA.120.049268. Epub 2020 Sep 8. Circulation. 2020. PMID: 32897751 Free PMC article. No abstract available.
Fat-to-heart crosstalk in health and disease.
Lodewijks F, McKinsey TA, Robinson EL. Lodewijks F, et al. Front Genet. 2023 Mar 24;14:990155. doi: 10.3389/fgene.2023.990155. eCollection 2023. Front Genet. 2023. PMID: 37035745 Free PMC article. Review.
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