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Profiling the proximal proteome of the activated μ-opioid receptor.
Polacco BJ, Lobingier BT, Blythe EE, Abreu N, Khare P, Howard MK, Gonzalez-Hernandez AJ, Xu J, Li Q, Novy B, Naing ZZC, Shoichet BK, Coyote-Maestas W, Levitz J, Krogan NJ, Von Zastrow M, Hüttenhain R. Polacco BJ, et al. Nat Chem Biol. 2024 Sep;20(9):1133-1143. doi: 10.1038/s41589-024-01588-3. Epub 2024 Mar 25. Nat Chem Biol. 2024. PMID: 38528119 Free PMC article.
Selective targeting of mu opioid receptors to primary cilia.
Fagan RR, Lee DF, Geron M, Scherrer G, von Zastrow M, Ehrlich AT. Fagan RR, et al. Cell Rep. 2024 May 28;43(5):114164. doi: 10.1016/j.celrep.2024.114164. Epub 2024 Apr 27. Cell Rep. 2024. PMID: 38678559 Free PMC article.
Gαs is dispensable for β-arrestin coupling but dictates GRK selectivity and is predominant for gene expression regulation by β2-adrenergic receptor.
Burghi V, Paradis JS, Officer A, Adame-Garcia SR, Wu X, Matthees ESF, Barsi-Rhyne B, Ramms DJ, Clubb L, Acosta M, Tamayo P, Bouvier M, Inoue A, von Zastrow M, Hoffmann C, Gutkind JS. Burghi V, et al. J Biol Chem. 2023 Nov;299(11):105293. doi: 10.1016/j.jbc.2023.105293. Epub 2023 Sep 27. J Biol Chem. 2023. PMID: 37774973 Free PMC article.
15 results