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An E3-ligase-based method for ablating inhibitory synapses.
Gross GG, Straub C, Perez-Sanchez J, Dempsey WP, Junge JA, Roberts RW, Trinh le A, Fraser SE, De Koninck Y, De Koninck P, Sabatini BL, Arnold DB. Gross GG, et al. Nat Methods. 2016 Aug;13(8):673-8. doi: 10.1038/nmeth.3894. Epub 2016 Jun 6. Nat Methods. 2016. PMID: 27271196 Free PMC article.
Podoplanin negatively regulates CD4+ effector T cell responses.
Peters A, Burkett PR, Sobel RA, Buckley CD, Watson SP, Bettelli E, Kuchroo VK. Peters A, et al. J Clin Invest. 2015 Jan;125(1):129-40. doi: 10.1172/JCI74685. Epub 2014 Nov 21. J Clin Invest. 2015. PMID: 25415436 Free PMC article.