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Analysis of proteome-wide degradation dynamics in ALS SOD1 iPSC-derived patient neurons reveals disrupted VCP homeostasis.
Tsioras K, Smith KC, Edassery SL, Garjani M, Li Y, Williams C, McKenna ED, Guo W, Wilen AP, Hark TJ, Marklund SL, Ostrow LW, Gilthorpe JD, Ichida JK, Kalb RG, Savas JN, Kiskinis E. Tsioras K, et al. Cell Rep. 2023 Oct 31;42(10):113160. doi: 10.1016/j.celrep.2023.113160. Epub 2023 Sep 29. Cell Rep. 2023. PMID: 37776851 Free PMC article.
L3MBTL1 regulates ALS/FTD-associated proteotoxicity and quality control.
Lu J, Periz G, Lu YN, Tang Q, Liu Y, Zhang T, Shah Y, Thombre R, Aljumaah R, Li W, Mojsilovic-Petrovic J, Ji Y, Johnson K, Kalb R, Wang J. Lu J, et al. Nat Neurosci. 2019 Jun;22(6):875-886. doi: 10.1038/s41593-019-0384-5. Epub 2019 May 6. Nat Neurosci. 2019. PMID: 31061493 Free PMC article.
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